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Development Status
US Approved Rx
9
Possibly Marketed Outside US
8
US Previously Marketed
2
Other
1
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Primary Target
Norepinephrine transporter
5
Serotonin transporter
5
Serotonin 1a (5-HT1a) receptor
3
Serotonin 2a (5-HT2a) receptor
3
Serotonin (5-HT) receptor
2
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Highest Phase
Approved
12
Phase II
1
Phase III
1
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Approval Year
Unknown
9
1971
1
1981
1
1984
1
1993
1
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Condition
Major depressive disorder
9
Depression
4
Fibromyalgia
2
Insomnia
2
Alzheimer’s disease
1
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Treatment Modality
Primary
15
Palliative
2
Preventing
1
Secondary
1
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CNS Activity
CNS Active
13
CNS Penetrant
2
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Originator
Bristol-Myers Squibb
2
Wyeth
2
Aziende Chimiche Riunite Angelini Francesco
1
Cambridge University
1
Ek, A.|Witkop, B.
1
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Substance Class
Chemical
19
Concept
1
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Code System
CAS
20
EVMPD
20
WHO-ATC
20
WHO-VATC
20
ChEMBL
19
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ATC Level 1
NERVOUS SYSTEM
20
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ATC Level 2
PSYCHOANALEPTICS
20
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ATC Level 3
ANTIDEPRESSANTS
20
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ATC Level 4
Other antidepressants
20
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Substance Form
Principal Form
15
Salts, Hydrates, Esters, etc.
4
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Search results for
"ATC|NERVOUS SYSTEM|PSYCHOANALEPTICS|ANTIDEPRESSANTS|Other antidepressants"
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GEPIRONE
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JW5Y7B8Z18
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Other
Class (Stereo):
CHEMICAL (ACHIRAL)
VILOXAZINE
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5I5Y2789ZF
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CHEMICAL (RACEMIC)
VILAZODONE
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S239O2OOV3
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CHEMICAL (ACHIRAL)
MILNACIPRAN
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G56VK1HF36
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CHEMICAL (RACEMIC)
DESVENLAFAXINE
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NG99554ANW
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Class (Stereo):
CHEMICAL (RACEMIC)
DULOXETINE
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O5TNM5N07U
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Class (Stereo):
CHEMICAL (ABSOLUTE)
VENLAFAXINE
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GRZ5RCB1QG
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Class (Stereo):
CHEMICAL (RACEMIC)
TRAZODONE
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YBK48BXK30
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Class (Stereo):
CHEMICAL (ACHIRAL)
TRYPTOPHAN
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8DUH1N11BX
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Class (Stereo):
CHEMICAL (ABSOLUTE)
OXAFLOZANE
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V4WLW77V5Q
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Other
Class (Stereo):
CHEMICAL (RACEMIC)
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