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Development Status
US Previously Marketed
14
Possibly Marketed Outside US
13
US Approved Rx
10
US Approved OTC
9
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Primary Target
Histamine H1 receptor
38
Cytochrome P450 2D6
3
Muscarinic acetylcholine receptor
3
Cytochrome P450 3A4
2
HERG
2
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Highest Phase
Approved
37
Not Provided
1
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Approval Year
Unknown
13
1959
4
1948
3
1947
2
1953
2
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Condition
Allergic rhinitis
12
Seasonal allergic rhinitis
8
Urticaria
8
Perennial allergic rhinitis
7
Allergic conjunctivitis
6
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Treatment Modality
Primary
26
Palliative
15
Preventing
2
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CNS Activity
CNS Active
15
CNS Non-penetrant
10
CNS Penetrant
8
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Originator
Merck Sharp & Dohme
2
Sandoz
2
UCB
2
Almirall
1
Asta-Werke
1
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Substance Class
Chemical
46
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INN Stem
Chemical substance(-ine)
1
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Code System
CAS
46
DRUG BANK
46
DRUG CENTRAL
46
FDA UNII
46
WHO-ATC
46
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ATC Level 1
RESPIRATORY SYSTEM
46
DERMATOLOGICALS
8
SENSORY ORGANS
3
VARIOUS
1
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ATC Level 2
ANTIHISTAMINES FOR SYSTEMIC USE
46
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
8
OPHTHALMOLOGICALS
3
NASAL PREPARATIONS
2
ALL OTHER THERAPEUTIC PRODUCTS
1
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ATC Level 3
ANTIHISTAMINES FOR SYSTEMIC USE
46
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
8
DECONGESTANTS AND ANTIALLERGICS
3
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
2
ALL OTHER THERAPEUTIC PRODUCTS
1
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ATC Level 4
Other antihistamines for systemic use
19
Antihistamines for topical use
8
Aminoalkyl ethers
7
Phenothiazine derivatives
7
Piperazine derivatives
6
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Substance Form
Principal Form
43
Salts, Hydrates, Esters, etc.
3
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Search results for
"ATC|RESPIRATORY SYSTEM|ANTIHISTAMINES FOR SYSTEMIC USE|ANTIHISTAMINES FOR SYSTEMIC USE"
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EPINASTINE
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Q13WX941EF
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Class (Stereo):
CHEMICAL (RACEMIC)
KETOTIFEN
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X49220T18G
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CHEMICAL (ACHIRAL)
AZELASTINE
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ZQI909440X
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CHEMICAL (RACEMIC)
LEVOCETIRIZINE
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6U5EA9RT2O
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CHEMICAL (ABSOLUTE)
LORATADINE
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7AJO3BO7QN
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Class (Stereo):
CHEMICAL (ACHIRAL)
CETIRIZINE
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YO7261ME24
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Class (Stereo):
CHEMICAL (RACEMIC)
CLEMASTINE
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95QN29S1ID
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CHEMICAL (ABSOLUTE)
TRIMETHOBENZAMIDE
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W2X096QY97
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CHEMICAL (ACHIRAL)
PROMETHAZINE
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FF28EJQ494
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Class (Stereo):
CHEMICAL (RACEMIC)
DEXBROMPHENIRAMINE
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75T64B71RP
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