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Development Status
US Approved Rx
179
US Previously Marketed
21
US Approved OTC
4
Possibly Marketed Outside US
3
Other
2
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Primary Target
Glucocorticoid receptor
20
Muscarinic acetylcholine receptor M3
17
Mu opioid receptor
16
Muscarinic acetylcholine receptor M1
13
Beta-2 adrenergic receptor
12
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Highest Phase
Approved
188
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Approval Year
1956
4
1957
4
1961
4
1977
6
1981
4
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Condition
Hypertension
22
Asthma
9
Pain
9
Gastroesophageal reflux disease
8
Chronic obstructive pulmonary disease
7
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Treatment Modality
Primary
142
Palliative
42
Preventing
21
Curative
8
Secondary
5
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CNS Activity
CNS Active
62
CNS Penetrant
55
CNS Non-penetrant
24
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Originator
Pfizer
8
Boehringer Ingelheim
7
Eli Lilly
7
GlaxoSmithKline
4
Merck
4
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Substance Class
Chemical
185
Protein
18
Mixture
4
Concept
2
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Code System
CAS
209
NDF-RT
209
RXCUI
208
FDA UNII
207
DRUG BANK
206
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Protein Type
MONOCLONAL ANTIBODY
7
CYTOKINE
1
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ATC Level 1
CARDIOVASCULAR SYSTEM
42
NERVOUS SYSTEM
42
ALIMENTARY TRACT AND METABOLISM
39
SENSORY ORGANS
31
RESPIRATORY SYSTEM
29
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ATC Level 2
OPHTHALMOLOGICALS
31
ANALGESICS
18
CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
18
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
15
NASAL PREPARATIONS
13
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ATC Level 3
CORTICOSTEROIDS, PLAIN
18
ANTIINFLAMMATORY AGENTS
13
DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
12
OPIOIDS
12
ADRENERGICS, INHALANTS
11
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ATC Level 4
Glucocorticoids
11
Corticosteroids
10
Corticosteroids, plain
10
Corticosteroids, potent (group III)
10
Anticholinergics
8
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Substance Form
Principal Form
191
Salts, Hydrates, Esters, etc.
16
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Search results for
"Cellular or Molecular Interactions [MoA]|Receptor Interactions [MoA]"
in
comments
(approximate match)
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MILNACIPRAN
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G56VK1HF36
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Class (Stereo):
CHEMICAL (RACEMIC)
TAPENTADOL
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H8A007M585
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ELTROMBOPAG
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S56D65XJ9G
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CHEMICAL (ACHIRAL)
DESVENLAFAXINE
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NG99554ANW
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CHEMICAL (RACEMIC)
ALVIMOPAN ANHYDROUS
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Q153V49P3Z
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CHEMICAL (ABSOLUTE)
SILODOSIN
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CUZ39LUY82
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Maraviroc
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MD6P741W8A
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CHEMICAL (ABSOLUTE)
VARENICLINE
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W6HS99O8ZO
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CHEMICAL (ACHIRAL)
RAMELTEON
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901AS54I69
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Class (Stereo):
CHEMICAL (ABSOLUTE)
TROSPIUM
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T4Y8ORK057
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