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Development Status
US Approved Rx
19
US Previously Marketed
3
Possibly Marketed Outside US
2
US Approved OTC
2
Other
1
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Primary Target
Vitamin D receptor
6
Oxidative Stress
2
Alpha-1-antichymotrypsin
1
C55-isoprenyl pyrophosphate
1
Complement and Coagulation Cascades
1
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Highest Phase
Approved
24
Phase III
1
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Approval Year
1921
7
1947
5
1940
3
1952
2
Unknown
2
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Condition
Hypoparathyroidism
2
Megaloblastic anemia
2
Unknown
2
Vitamin K deficiency
2
Advanced colorectal cancer
1
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Treatment Modality
Primary
14
Preventing
9
Palliative
7
Curative
4
Secondary
4
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CNS Activity
CNS Active
8
CNS Penetrant
8
CNS Non-penetrant
1
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Originator
University of Wisconsin-Madison
2
Abbott
1
Askew, F.A. et al.
1
Blunt, J.W|DeLuca, H.F.|Schnoes, H.K.
1
Burroughs Wellcome Fund
1
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Substance Class
Chemical
22
Mixture
4
Concept
1
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Code System
LIVERTOX
27
RXCUI
27
CAS
26
CHEBI
26
DRUG BANK
26
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ATC Level 1
ALIMENTARY TRACT AND METABOLISM
10
BLOOD AND BLOOD FORMING ORGANS
6
DERMATOLOGICALS
4
SENSORY ORGANS
3
VARIOUS
3
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ATC Level 2
VITAMINS
9
ANTIANEMIC PREPARATIONS
3
OPHTHALMOLOGICALS
3
ALL OTHER THERAPEUTIC PRODUCTS
2
ANTIHEMORRHAGICS
2
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ATC Level 3
VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
6
VITAMIN B12 AND FOLIC ACID
3
ALL OTHER THERAPEUTIC PRODUCTS
2
ANTI-PARATHYROID AGENTS
2
IRON PREPARATIONS
2
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ATC Level 4
Vitamin D and analogues
5
Iron in other combinations
2
Other anti-parathyroid agents
2
Other ophthalmologicals
2
Other plain vitamin preparations
2
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Substance Form
Principal Form
21
Salts, Hydrates, Esters, etc.
5
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Search results for
"LiverTox|HDS
in
comments
(approximate match)
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DOXERCALCIFEROL
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3DIZ9LF5Y9
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Class (Stereo):
CHEMICAL (ABSOLUTE)
PARICALCITOL
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6702D36OG5
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CHEMICAL (ABSOLUTE)
CALCITRIOL
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FXC9231JVH
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CHEMICAL (ABSOLUTE)
LEUCOVORIN
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Q573I9DVLP
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CHEMICAL (EPIMERIC)
LEVOLEUCOVORIN
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990S25980Y
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CHEMICAL (ABSOLUTE)
ASCORBIC ACID
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PQ6CK8PD0R
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CHEMICAL (ABSOLUTE)
CYANOCOBALAMIN
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P6YC3EG204
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DEXPANTHENOL
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1O6C93RI7Z
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PYRIDOXINE
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KV2JZ1BI6Z
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CHEMICAL (ACHIRAL)
Folic acid
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935E97BOY8
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