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Development Status
Investigational
482
US Approved Rx
232
Possibly Marketed Outside US
111
Other
79
US Previously Marketed
33
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Primary Target
DNA
84
Vascular endothelial growth factor receptor 2
34
Tubulin
31
DNA topoisomerase II
30
Stem cell growth factor receptor
26
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Highest Phase
Approved
274
Phase II
133
Phase III
84
Phase I
25
Not Provided
2
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Approval Year
Unknown
670
2013
11
2015
11
2017
10
2018
10
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Condition
Breast cancer
83
Non-small cell lung cancer
77
Ovarian cancer
35
Multiple myeloma
32
Prostate cancer
29
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Treatment Modality
Primary
496
Palliative
48
Curative
17
Secondary
16
Preventing
14
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CNS Activity
CNS Penetrant
170
CNS Active
79
CNS Non-penetrant
57
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Originator
Novartis
21
Eli Lilly
18
Pfizer
18
Wyeth
13
AstraZeneca
12
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Substance Class
Chemical
885
Protein
37
Mixture
13
Structurally Diverse
3
Concept
2
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INN Stem
Tyrosine-kinase inhibitors(-tinib)
1
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Code System
NCI_THESAURUS
942
FDA UNII
940
CAS
935
PUBCHEM
888
EPA CompTox
771
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Protein Type
MONOCLONAL ANTIBODY
14
MONOCLONAL ANTIBODY CONJUGATE
8
CYTOKINE
2
BISPECIFIC ANTIBODY
1
FAB
1
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
147
DERMATOLOGICALS
15
ANTIINFECTIVES FOR SYSTEMIC USE
12
VARIOUS
9
SENSORY ORGANS
7
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ATC Level 2
ANTINEOPLASTIC AGENTS
125
ANTIVIRALS FOR SYSTEMIC USE
10
IMMUNOSUPPRESSANTS
9
IMMUNOSTIMULANTS
8
ENDOCRINE THERAPY
6
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
64
ALKYLATING AGENTS
24
ANTIMETABOLITES
15
CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
12
PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
11
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ATC Level 4
Protein kinase inhibitors
40
Other antineoplastic agents
18
Anthracyclines and related substances
8
Antivirals
7
Nitrogen mustard analogues
7
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Substance Form
Principal Form
678
Salts, Hydrates, Esters, etc.
262
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Search results for
"Pharmacologic Substance[C1909]|Antineoplastic Agent[C274]"
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ELACESTRANT
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FM6A2627A8
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
FRUQUINTINIB
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49DXG3M5ZW
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CHEMICAL (ACHIRAL)
CAPIVASERTIB
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WFR23M21IE
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QUIZARTINIB
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7LA4O6Q0D3
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CHEMICAL (ACHIRAL)
Palovarotene
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28K6I5M16G
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Class (Stereo):
CHEMICAL (ACHIRAL)
TRILACICLIB
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U6072DO9XG
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Class (Stereo):
CHEMICAL (ACHIRAL)
TEPOTINIB
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1IJV77EI07
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Class (Stereo):
CHEMICAL (ACHIRAL)
PEMIGATINIB
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Y6BX7BL23K
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Class (Stereo):
CHEMICAL (ACHIRAL)
LURBINECTEDIN
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2CN60TN6ZS
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Class (Stereo):
CHEMICAL (ABSOLUTE)
SELUMETINIB
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6UH91I579U
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Class (Stereo):
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