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Development Status
US Approved Rx
24
Possibly Marketed Outside US
20
US Previously Marketed
4
Other
1
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Primary Target
Serotonin transporter
15
Norepinephrine transporter
12
Histamine H1 receptor
4
Monoamine oxidase A
4
Serotonin 2a (5-HT2a) receptor
4
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Highest Phase
Approved
36
Phase II
1
Phase III
1
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Approval Year
Unknown
21
1959
2
1980
2
1994
2
1955
1
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Condition
Depression
16
Major depressive disorder
16
Obsessive-compulsive disorder
5
Generalized anxiety disorder
4
Panic disorder
3
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Treatment Modality
Primary
40
Palliative
3
Preventing
1
Secondary
1
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CNS Activity
CNS Active
37
CNS Penetrant
4
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Originator
Bristol-Myers Squibb
2
Eli Lilly
2
Hoffman-La Roche
2
Lundbeck
2
Merck
2
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Substance Class
Chemical
47
Concept
1
Mixture
1
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Code System
CAS
49
EVMPD
49
WHO-ATC
49
WHO-VATC
49
ChEMBL
48
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ATC Level 1
NERVOUS SYSTEM
49
DERMATOLOGICALS
1
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ATC Level 2
PSYCHOANALEPTICS
49
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
1
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ATC Level 3
ANTIDEPRESSANTS
49
PSYCHOLEPTICS AND PSYCHOANALEPTICS IN COMBINATION
2
ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
1
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ATC Level 4
Other antidepressants
20
Non-selective monoamine reuptake inhibitors
17
Selective serotonin reuptake inhibitors
7
Monoamine oxidase inhibitors, non-selective
3
Antidepressants in combination with psycholeptics
2
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Substance Form
Principal Form
43
Salts, Hydrates, Esters, etc.
5
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Search results for
"VATC|PSYCHOANALEPTICS|ANTIDEPRESSANTS"
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GEPIRONE
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JW5Y7B8Z18
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Class (Stereo):
CHEMICAL (ACHIRAL)
VILOXAZINE
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5I5Y2789ZF
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CHEMICAL (RACEMIC)
VILAZODONE
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S239O2OOV3
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CHEMICAL (ACHIRAL)
MILNACIPRAN
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G56VK1HF36
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CHEMICAL (RACEMIC)
DESVENLAFAXINE
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NG99554ANW
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CHEMICAL (RACEMIC)
DULOXETINE
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O5TNM5N07U
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CHEMICAL (ABSOLUTE)
ESCITALOPRAM
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4O4S742ANY
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CHEMICAL (ABSOLUTE)
CITALOPRAM
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0DHU5B8D6V
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CHEMICAL (RACEMIC)
FLUVOXAMINE
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O4L1XPO44W
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CHEMICAL (ACHIRAL)
VENLAFAXINE
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GRZ5RCB1QG
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