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Details

Stereochemistry ACHIRAL
Molecular Formula C28H24FN3O5
Molecular Weight 501.5057
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CABOZANTINIB

SMILES

COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3)=CC=NC2=C1

InChI

InChIKey=ONIQOQHATWINJY-UHFFFAOYSA-N
InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
CABOZANTINIB
DASH   INN   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
1,1-CYCLOPROPANEDICARBOXAMIDE, N-(4-((6,7-DIMETHOXY-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-
Systematic Name English
Cabozantinib [WHO-DD]
Common Name English
BMS-907351 FREE BASE
Code English
XL-184 FREE BASE
Code English
CABOZANTINIB [VANDF]
Common Name English
cabozantinib [INN]
Common Name English
CABOZANTINIB [MI]
Common Name English
N-(4-((6,7-DIMETHOXY-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-1,1-CYCLOPROPANEDICARBOXAMIDE
Systematic Name English
1,1-CYCLOPROPANEDICARBOXAMIDE, N'-(4-((6,7-DIMETHOXY-4-QUINOLINYL)OXY)PHENYL)-N-(4-FLUOROPHENYL)-
Systematic Name English
CABOZANTINIB [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1967
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
NCI_THESAURUS C1742
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
FDA ORPHAN DRUG 297109
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
NCI_THESAURUS C129825
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
LIVERTOX NBK548279
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
NDF-RT N0000175605
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
EMA ASSESSMENT REPORTS COMETRIQ (AUTHORIZED: THYROID NEOPLASMS)
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
WHO-ATC L01XE26
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
NCI_THESAURUS C93259
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
FDA ORPHAN DRUG 552916
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
Code System Code Type Description
WIKIPEDIA
Cabozantinib
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
MERCK INDEX
m11686
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
USAN
WW-154
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
DAILYMED
1C39JW444G
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
DRUG BANK
DB08875
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
EVMPD
SUB93452
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
IUPHAR
5887
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
INN
9297
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
ChEMBL
CHEMBL2105717
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
RXCUI
1363268
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY RxNorm
DRUG CENTRAL
4715
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
NCI_THESAURUS
C52200
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
FDA UNII
1C39JW444G
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
PUBCHEM
25102847
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
LACTMED
Cabozantinib
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
CAS
849217-68-1
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
EPA CompTox
DTXSID10233968
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
SMS_ID
100000141570
Created by admin on Fri Dec 15 19:29:29 UTC 2023 , Edited by admin on Fri Dec 15 19:29:29 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of CABOZANTINIB
SALT/SOLVATE (PARENT)
Structure of CABOZANTINIB S-MALATE
SALT/SOLVATE (PARENT)
Structure of Cabozantinib Hydrochloride
NIH
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