U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C37H48N6O5S2
Molecular Weight 720.944
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RITONAVIR

SMILES

CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)CC4=CC=CC=C4

InChI

InChIKey=NCDNCNXCDXHOMX-XGKFQTDJSA-N
InChI=1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
RITONAVIR
EMA EPAR   EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   VANDF   WHO-DD   WHO-IP  
INN   USAN  
Official Name English
NORVIR
Brand Name English
RITONAVIR [VANDF]
Common Name English
RITONAVIR [MI]
Common Name English
VIRITON
Brand Name English
EMPETUS
Brand Name English
PAXLOVID COMPONENT RITONAVIR
Brand Name English
ritonavir [INN]
Common Name English
ABBOTT-84538
Code English
VIEKIRAX COMPONENT RITONAVIR
Brand Name English
RITOVIR
Brand Name English
KALETRA COMPONENT RITONAVIR
Common Name English
RITONAVIR [HSDB]
Common Name English
RITONAVIR [USP-RS]
Common Name English
NSC-693184
Code English
ABT-538
Code English
RITONAVIR COMPONENT OF PAXLOVID
Brand Name English
RITONAVIR COMPONENT OF VIEKIRAX
Brand Name English
RTV
Common Name English
RITONAVIR [EMA EPAR]
Common Name English
RITONAVIR [JAN]
Common Name English
Ritonavir [WHO-DD]
Common Name English
RITONAVIR COMPONENT OF KALETRA
Common Name English
RITONAVIR [ORANGE BOOK]
Common Name English
RITONAVIRUM [WHO-IP LATIN]
Common Name English
A-84538
Code English
RITOMUNE
Brand Name English
RITONAVIR RELATED COMPOUNDS MIXTURE
USP-RS  
Common Name English
2,7,10,12-TETRAAZATRIDECANOIC ACID, 4-HYDROXY-12-METHYL-9-(1-METHYLETHYL)-13-(2-(1-METHYLETHYL)-4-THIAZOLYL)-8,11-DIOXO-3,6-BIS(PHENYLMETHYL)-, 5-THIAZOLYLMETHYL ESTER, (3S,4S,6S,9S)-
Systematic Name English
RITONAVIR [MART.]
Common Name English
2,4,7,12-TETRAAZATRIDECAN-13-OIC ACID, 10-HYDROXY-2-METHYL-5-(1-METHYLETHYL)-1-(2-(1-METHYLETHYL)-4-THIAZOLYL)-3,6-DIOXO-8,11-BIS(PHENYLMETHYL)-5-THIAZOLYLMETHYL ESTER (5S-(5R*,8R*,10R*,11R*))-
Common Name English
RITONAVIR [USP IMPURITY]
Common Name English
RITONAVIR [USP MONOGRAPH]
Common Name English
RITONAVIR RELATED COMPOUNDS MIXTURE [USP-RS]
Common Name English
RITONAVIR [WHO-IP]
Common Name English
VIEKIRAX
Brand Name English
5-Thiazolylmethyl [(αS)-α-[(1S,3S)-1-hydroxy-3-[(2S)-2-[3-[(2-isopropyl-4-thiazolyl)methyl]-3-methylureido]-3-methylbutyramido]-4-phenylbutyl]phenethyl]carbamate
Common Name English
RITONAVIR [USAN]
Common Name English
Classification Tree Code System Code
LIVERTOX NBK548747
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AR10
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AE03
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-VATC QJ05AE03
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-VATC QJ05AR10
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AP52
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
EMA ASSESSMENT REPORTS LOPINAVIR (AUHTORIZED: HIV INFECTIONS)
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AX66
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
FDA ORPHAN DRUG 549816
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
NCI_THESAURUS C97366
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
FDA ORPHAN DRUG 509215
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.4.2.3
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
EMA ASSESSMENT REPORTS KALETRA (AUTHORIZED: HIV INFECTIONS)
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.4.2.3 (LPV/R)
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AR23
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AP53
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
NDF-RT N0000191001
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
NDF-RT N0000175889
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
FDA ORPHAN DRUG 484715
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
NDF-RT N0000000246
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
EMA ASSESSMENT REPORTS VIEKIRAX (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
WHO-ATC J05AX67
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
EMA ASSESSMENT REPORTS NORVIR (AUTHORIZED: HIV INFECTIONS)
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
Code System Code Type Description
WHO INTERNATIONAL PHARMACOPEIA
RITONAVIR
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Description: A white or almost white powder. Solubility: Practically insoluble in water, freely soluble in methanol R, sparingly soluble in acetone R and very slightly soluble in acetonitrile R. Category: Antiretroviral (Protease Inhibitor). Storage: Ritonavir should be kept in a well-closed container, protected from light. Additional information: Ritonavir may exhibit polymorphism. Requirements: Ritonavir contains not less than 98.5 % and not more than 101.0 % of C37H48N6O5S2, calculated with reference to the dried substance.
FDA UNII
O3J8G9O825
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
ChEMBL
CHEMBL163
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
RS_ITEM_NUM
1604803
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
INN
7449
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
EVMPD
SUB10342MIG
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
WIKIPEDIA
RITONAVIR
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
RXCUI
85762
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY RxNorm
NDF-RT
N0000182137
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 2D6 Inhibitors [MoA]
NDF-RT
N0000182141
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 3A4 Inhibitors [MoA]
NDF-RT
N0000187064
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 2B6 Inducers [MoA]
DRUG BANK
DB00503
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
MESH
D019438
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
LACTMED
Ritonavir
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000185607
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 2C19 Inducers [MoA]
DRUG CENTRAL
2391
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000191266
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 1A2 Inducers [MoA]
SMS_ID
100000089167
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000190113
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Breast Cancer Resistance Protein Inhibitors [MoA]
CHEBI
45409
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000185507
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 2C9 Inducers [MoA]
EPA CompTox
DTXSID1048627
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000190117
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY UDP Glucuronosyltransferases Inducers [MoA]
NDF-RT
N0000190118
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 3A Inducers [MoA]
NSC
693184
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
DAILYMED
O3J8G9O825
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
MERCK INDEX
m9636
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Merck Index
NDF-RT
N0000190114
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY Cytochrome P450 3A Inhibitors [MoA]
PUBCHEM
392622
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
HSDB
7160
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
IUPHAR
8804
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NCI_THESAURUS
C1609
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
CAS
155213-67-5
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
NDF-RT
N0000185503
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY P-Glycoprotein Inhibitors [MoA]
USAN
GG-103
Created by admin on Fri Dec 15 15:29:49 UTC 2023 , Edited by admin on Fri Dec 15 15:29:49 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of RITONAVIR
METABOLITE ACTIVE (PARENT)
Structure of HYDROXYRITONAVIR
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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