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Details

Stereochemistry RACEMIC
Molecular Formula C17H18F3NO
Molecular Weight 309.3261
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUOXETINE

SMILES

CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C2=CC=CC=C2

InChI

InChIKey=RTHCYVBBDHJXIQ-UHFFFAOYSA-N
InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3

HIDE SMILES / InChI
Molecular Formula C17H18F3NO
Molecular Weight 309.3261
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:36:36 UTC 2023
Edited
by admin
on Fri Dec 15 15:36:36 UTC 2023
Record UNII
01K63SUP8D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUOXETINE
INN   MI   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
fluoxetine [INN]
Common Name English
(±)-N-METHYL-3-PHENYL-3-((.ALPHA.,ALPHA.,.ALPHA.-TRIFLUORO-P-TOLYL)OXY)PROPYLAMINE
Common Name English
FLUOXETIN RATIOPHARM
Common Name English
DL-N-METHYL-3-(P-TRIFLUOROMETHYLPHENOXY)-3-PHENYLPROPYLAMINE
Common Name English
FLUOXETINE [USAN]
Common Name English
NSC-283480
Code English
NSC-758685
Code English
Fluoxetine [WHO-DD]
Common Name English
FLUOXETINE [EMA EPAR VETERINARY]
Common Name English
FLUOXETINE [VANDF]
Common Name English
N-METHYL-.GAMMA.-(4-(TRIFLUOROMETHYL)PHENOXY)BENZENEPROPANAMINE
Systematic Name English
FLUOXETINE [MI]
Common Name English
FLUVAL
Common Name English
BENZENEPROPANAMINE, N-METHYL-G-(4-(TRIFLUOROMETHYL)PHENOXY)-, (±)-
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 183504
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
NDF-RT N0000000109
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-ATC N06AB03
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
EMA VETERINARY ASSESSMENT REPORTS RECONCILE [AUTHORIZED]
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
FDA ORPHAN DRUG 123199
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
LIVERTOX NBK548010
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-ATC N06CA03
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-VATC QN06AB03
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 24.2.1
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.4
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
NCI_THESAURUS C94725
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
CFR 21 CFR 520.980
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
NCI_THESAURUS C265
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
NDF-RT N0000175696
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
WHO-VATC QN06CA03
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
Code System Code Type Description
WIKIPEDIA
FLUOXETINE
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
MERCK INDEX
m5487
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY Merck Index
CAS
54910-89-3
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
ChEMBL
CHEMBL41
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
EVMPD
SUB07723MIG
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
FDA UNII
01K63SUP8D
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
DAILYMED
01K63SUP8D
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
DRUG CENTRAL
1209
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
NSC
283480
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
RXCUI
4493
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C506
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
EPA CompTox
DTXSID7023067
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
IUPHAR
203
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
CHEBI
5118
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
PUBCHEM
3386
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
INN
3883
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
DRUG BANK
DB00472
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
MESH
D005473
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
NSC
758685
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
LACTMED
Fluoxetine
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
SMS_ID
100000092819
Created by admin on Fri Dec 15 15:36:36 UTC 2023 , Edited by admin on Fri Dec 15 15:36:36 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 2C9
METABOLIC ENZYME -> INHIBITOR
SODIUM-DEPENDENT SEROTONIN TRANSPORTER
TARGET -> INHIBITOR
CYTOCHROME P450 2D6
METABOLIC ENZYME -> INHIBITOR
Structure of FLUOXETINE OXALATE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 2C19
METABOLIC ENZYME -> SUBSTRATE
Structure of FLUOXETINE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of 4-TRIFLUOROMETHYLPHENOL
METABOLITE -> PARENT
Structure of NORFLUOXETINE
METABOLITE ACTIVE -> PARENT
Related Record Type Details
Structure of FLUOXETINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MAXIMUM TOLERATED DOSE TOXICITY RAPID METABOLIZERS OR THOSE WITH INADEQUATE RESPONSE AFTER 8 WEEKS

Tmax PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC NORFLUOXETINE
PHARMACOKINETIC
NORFLUOXETINE, LIVER CIRRHOSIS
PHARMACOKINETIC
LIVER CIRRHOSIS
PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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