AFOXOLANER

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C26H17ClF9N3O3
Molecular Weight	625.87
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AFOXOLANER

Structure Search

SMILES

FC(F)(F)CNC(=O)CNC(=O)C1=C2C=CC=CC2=C(C=C1)C3=NOC(C3)(C4=CC(=CC(Cl)=C4)C(F)(F)F)C(F)(F)F

InChI

InChIKey=OXDDDHGGRFRLEE-UHFFFAOYSA-N

InChI=1S/C26H17ClF9N3O3/c27-15-8-13(7-14(9-15)25(31,32)33)23(26(34,35)36)10-20(39-42-23)18-5-6-19(17-4-2-1-3-16(17)18)22(41)37-11-21(40)38-12-24(28,29)30/h1-9H,10-12H2,(H,37,41)(H,38,40)

HIDE SMILES / InChI

Molecular Formula	C26H17ClF9N3O3
Molecular Weight	625.87
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:27:55 UTC 2023` Edited by `admin` on `Sat Dec 16 07:27:55 UTC 2023`
Record UNII	02L07H6D0U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AFOXOLANER

Official Name

English

AFOXOLANER [USAN]

Common Name

English

AFOXOLANER [GREEN BOOK]

Common Name

English

AFOXOLANER CONPONENT OF NEXGARD SPECTRA

Common Name

English

4-(5-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDROISOXAZOL-3-YL(-N- (2-OXO-2-((2,2,2-TRIFLUOROETHYL)AMINO)ETHYL(NAPHTHALENE-1-CARBOXAMIDE

Common Name

English

NEXGARD

Brand Name

English

1-NAPHTHALENECARBOXAMIDE, 4-(5-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-4,5-DIHYDRO-5- (TRIFLUOROMETHYL)-3-ISOXAZOLYL)-N-(2-OXO-2-((2,2,2-TRIFLUOROETHYL)AMINO)ETHYL)-

Common Name

English

NEXGARD SPECTRA CONPONENT AFOXOLANER

Brand Name

English

AH252723

Code

English

AFOXOLANER [EMA EPAR VETERINARY]

Common Name

English

A1443

Code

English

AFOXOLANER [MI]

Common Name

English

afoxolaner [INN]

Common Name

English

Classification Tree Code System Code

EMA VETERINARY ASSESSMENT REPORTS

NEXGARD SPECTRA [AUTHORIZED]

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

CFR

21 CFR 520.43

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

WHO-VATC

QP53BX04

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

EMA VETERINARY ASSESSMENT REPORTS

NEXGARD [AUTHORIZED]

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C171791

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

CAS

1093861-60-9

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

USAN

ZZ-56

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

MERCK INDEX

m11748

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

ALANWOOD

afoxolaner

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

SMS_ID

300000023671

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

EPA CompTox

DTXSID50148921

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

WIKIPEDIA

Afoxolaner

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

ChEMBL

CHEMBL2219412

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

FDA UNII

02L07H6D0U

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

INN

9697

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

PUBCHEM

25154249

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

DAILYMED

02L07H6D0U

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

RXCUI

1442093

Created by admin on Sat Dec 16 07:27:55 UTC 2023 , Edited by admin on Sat Dec 16 07:27:55 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					XK874NX18T

AFOXOLANER, (R)-

ENANTIOMER -> RACEMATE


					46658IQN7V

ENANTIOMER -> RACEMATE

Related Record Type Details


					02L07H6D0U

ACTIVE MOIETY