NEBIVOLOL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H25F2NO4
Molecular Weight	405.435
Optical Activity	( + / - )
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NEBIVOLOL

Structure Search

SMILES

[H][C@]1(CCC2=CC(F)=CC=C2O1)[C@H](O)CNC[C@@H](O)[C@@]3([H])CCC4=C(O3)C=CC(F)=C4

InChI

InChIKey=KOHIRBRYDXPAMZ-YHBROIRLSA-N

InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2/t17-,18-,21-,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H25F2NO4
Molecular Weight	405.435
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:54 UTC 2023` Edited by `admin` on `Fri Dec 15 15:40:54 UTC 2023`
Record UNII	030Y90569U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NEBIVOLOL

Official Name

English

NEBIVOLOL [VANDF]

Common Name

English

NEBIVOLOL COMPONENT OF BYVALSON

Common Name

English

nebivolol [INN]

Common Name

English

NEBIVOLOL [MI]

Common Name

English

NEBIVOLOL [MART.]

Common Name

English

NEBIVOLOL [USAN]

Common Name

English

R65,824

Code

English

Nebivolol [WHO-DD]

Common Name

English

NARBIVOLOL

Common Name

English

BYVALSON COMPONENT NEBIVOLOL

Common Name

English

R-65824

Code

English

(±)-Nebivolol

Common Name

English

2H-1-Benzopyran-2-methanol, α,α′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (αR,α′R,2R,2′S)-rel-

Systematic Name

English

rel-(αR,α′R,2R,2′S)-α,α′-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]

Systematic Name

English

Classification Tree Code System Code

LIVERTOX

NBK548386

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

NDF-RT

N0000175556

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-VATC

QC07AB12

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-ATC

C07FB12

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-ATC

C09DX05

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

NCI_THESAURUS

C29576

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-ATC

C07BB12

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-ATC

C07AB12

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

WHO-VATC

QC07BB12

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

Code System Code Type Description

SMS_ID

100000093044

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

DRUG CENTRAL

1887

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

DRUG BANK

DB04861

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

NCI_THESAURUS

C66221

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

PUBCHEM

189562

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

MERCK INDEX

m7786

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

Merck Index

USAN

Y-62

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

EVMPD

SUB09175MIG

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

DAILYMED

030Y90569U

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

FDA UNII

030Y90569U

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

ChEMBL

CHEMBL434394

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

LACTMED

Nebivolol

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

IUPHAR

7246

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

CAS

99200-09-6

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

NON-SPECIFIC STEREOCHEMISTRY

CHEBI

64022

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

RXCUI

31555

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID9040556

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

MESH

C052753

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

WIKIPEDIA

NEBIVOLOL

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

INN

5969

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

CAS

118457-14-0

Created by admin on Fri Dec 15 15:40:54 UTC 2023 , Edited by admin on Fri Dec 15 15:40:54 UTC 2023

PRIMARY

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CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

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CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

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BETA-1 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING

Amount:


					JGS34J7L9I

NEBIVOLOL HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					030Y90569U

NEBIVOLOL

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				IN THE EM POPULATION FASTED CONDITION ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC