ZOPICLONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H17ClN6O3
Molecular Weight	388.808
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ZOPICLONE

Structure Search

SMILES

CN1CCN(CC1)C(=O)OC2N(C(=O)C3=C2N=CC=N3)C4=CC=C(Cl)C=N4

InChI

InChIKey=GBBSUAFBMRNDJC-UHFFFAOYSA-N

InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3

HIDE SMILES / InChI

Molecular Formula	C17H17ClN6O3
Molecular Weight	388.808
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:14:22 UTC 2023` Edited by `admin` on `Sat Dec 16 17:14:22 UTC 2023`
Record UNII	03A5ORL08Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ZOPICLONE

Official Name

English

6-(5-CHLOROPYRID-2-YL)-5-(4-METHYLPIPERAZIN-1-YL)CARBONYLOXY-7-OXO-6,7-DIHYDRO-5H-PYRROLO(3,4-B)PYRAZINE

Systematic Name

English

ZOPICLONE [MART.]

Common Name

English

IMOVANE

Common Name

English

AMOBAN

Brand Name

English

Zopiclone [WHO-DD]

Common Name

English

ZOPICLONE [JAN]

Common Name

English

NSC-758463

Code

English

ZOPICLONE [MI]

Common Name

English

ZIMOVANE

Brand Name

English

4-METHYL-1-PIPERAZINECARBOXYLIC ACID ESTER WITH 6-(5-CHLORO-2-PYRIDYL)-6,7-DIHYDRO-7-HYDROXY-5H-PYRROLO(3,4-B)PYRAZIN-5-ONE

Common Name

English

ZOPICLONE [EP MONOGRAPH]

Common Name

English

RP-27267

Code

English

ZOPICLONE [EP IMPURITY]

Common Name

English

4-METHYL-1-PIPERAZINECARBOXYLIC ACID 6-(5-CHLORO-2-PYRIDINYL)-6,7-DIHYDRO-7-OXO-5H-PYRROLO(3,4-B)PYRAZIN-5-YL ESTER

Systematic Name

English

zopiclone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

DEA NO.

2784

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

WHO-VATC

QN05CF01

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

WHO-ATC

N05CF01

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

Code System Code Type Description

ECHA (EC/EINECS)

256-138-9

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

DRUG BANK

DB01198

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

CAS

43200-80-2

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

DRUG CENTRAL

2873

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

MERCK INDEX

m11663

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

Merck Index

FDA UNII

03A5ORL08Q

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

PUBCHEM

5735

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

EPA CompTox

DTXSID4041155

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

MESH

C515050

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

CHEBI

32315

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

EVMPD

SUB00188MIG

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

IUPHAR

7430

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

INN

4462

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

NCI_THESAURUS

C80279

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

CHEBI

53762

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

RXCUI

40001

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

RxNorm

NSC

758463

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

WIKIPEDIA

ZOPICLONE

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

ChEMBL

CHEMBL135400

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

SMS_ID

100000092519

Created by admin on Sat Dec 16 17:14:23 UTC 2023 , Edited by admin on Sat Dec 16 17:14:23 UTC 2023

PRIMARY

Related Record Type Details


					03A5ORL08Q

ZOPICLONE

EXCRETED UNCHANGED

Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:


					03A5ORL08Q

ZOPICLONE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					SB6JSG9LHB

ZOPICLONE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					L0423Z5LDW

CYTOCHROME P450 2C8

METABOLIC ENZYME -> SUBSTRATE


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR

Related Record Type Details


					DJL5TX7YTA

Desmethylzopiclone

METABOLITE -> PARENT

Amount:


					0XXQ8C2EK4

ZOPICLONE N-OXIDE

METABOLITE -> PARENT

Related Record Type Details


					5IHV56HP9P

RP-48497

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					68396623QX

RP-29307

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					0XXQ8C2EK4

ZOPICLONE N-OXIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					03A5ORL08Q

ZOPICLONE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC

ORAL BIOAVAILABILITY	PHARMACOKINETIC