PRUCALOPRIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H26ClN3O3
Molecular Weight	367.87
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRUCALOPRIDE

Structure Search

SMILES

COCCCN1CCC(CC1)NC(=O)C2=C3OCCC3=C(N)C(Cl)=C2

InChI

InChIKey=ZPMNHBXQOOVQJL-UHFFFAOYSA-N

InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)

HIDE SMILES / InChI

Molecular Formula	C18H26ClN3O3
Molecular Weight	367.87
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:38:52 UTC 2023` Edited by `admin` on `Fri Dec 15 16:38:52 UTC 2023`
Record UNII	0A09IUW5TP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PRUCALOPRIDE

Official Name

English

R-093877

Code

English

PRUCALOPRIDE [EMA EPAR]

Common Name

English

PRUCALOPRIDE [MI]

Common Name

English

R093877

Common Name

English

PRUCALOPRIDE [USAN]

Common Name

English

4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidyl]-7-benzofurancarboxamide

Systematic Name

English

Prucalopride [WHO-DD]

Common Name

English

PRUCALOPRIDE [MART.]

Common Name

English

prucalopride [INN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

A03AE04

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

NCI_THESAURUS

C47794

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

WHO-ATC

A06AX05

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

WHO-VATC

QA06AX05

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

Code System Code Type Description

FDA UNII

0A09IUW5TP

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

INN

7702

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

RXCUI

2107310

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

SMS_ID

100000080862

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

DAILYMED

0A09IUW5TP

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

EVMPD

SUB10155MIG

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

NCI_THESAURUS

C74386

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

MESH

C406662

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

DRUG CENTRAL

3502

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

EPA CompTox

DTXSID5057670

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

LACTMED

Prucalopride

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

ChEMBL

CHEMBL117287

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

IUPHAR

243

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

DRUG BANK

DB06480

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

WIKIPEDIA

PRUCALOPRIDE

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

USAN

YY-100

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

MERCK INDEX

m9285

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

Merck Index

CAS

179474-81-8

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

PUBCHEM

3052762

Created by admin on Fri Dec 15 16:38:52 UTC 2023 , Edited by admin on Fri Dec 15 16:38:52 UTC 2023

PRIMARY

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CUMULATIVE EXCRETION

Qualification:

FECAL

Amount:


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EXCRETED UNCHANGED

Qualification:

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PRUCALOPRIDE SUCCINATE

SALT/SOLVATE -> PARENT


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5-HYDROXYTRYPTAMINE RECEPTOR 4

TARGET -> AGONIST

Comments:

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Qualification:

EC50

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					0A09IUW5TP

CUMULATIVE EXCRETION

Qualification:

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Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Comments:

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Interaction Type:

BINDING

Amount:


					M8IYX9Z79V

PRUCALOPRIDE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

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O-DESMETHYL PRUCALOPRIDE ACID

METABOLITE -> PARENT

Comments:

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Qualification:

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					0A09IUW5TP

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC
Tmax	PHARMACOKINETIC				ROUTE OF ADMINISTRATION PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				DOSE PHARMACOKINETIC ROUTE OF ADMINISTRATION PHARMACOKINETIC
BREAST MILK/PLASMA RATIO	PHARMACOKINETIC				COMMENTS PHARMACOKINETIC