7-ETHYL-10-HYDROXYCAMPTOTHECIN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H20N2O5
Molecular Weight	392.4046
Optical Activity	( + )
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 7-ETHYL-10-HYDROXYCAMPTOTHECIN

Structure Search

SMILES

CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC5=CC=C(O)C=C15

InChI

InChIKey=FJHBVJOVLFPMQE-QFIPXVFZSA-N

InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H20N2O5
Molecular Weight	392.4046
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:42:23 UTC 2023` Edited by `admin` on `Fri Dec 15 15:42:23 UTC 2023`
Record UNII	0H43101T0J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

7-ETHYL-10-HYDROXYCAMPTOTHECIN

Common Name

English

1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4,11-DIETHYL-4,9-DIHYDROXY-, (4S)-

Systematic Name

English

SN 38 [WHO-DD]

Common Name

English

IRINOTECAN RELATED COMPOUND B [USP-RS]

Common Name

English

SN-38

Code

English

S-(+)-7-ETHYL-10-HYDROXYCAMPOTHECIN

Common Name

English

SN38	Locators: WHO-DD Sources:

Code

English

NK012

Code

English

NK-012

Code

English

CAMPTOTHECIN, 7-ETHYL-10-HYDROXY-

Common Name

English

IRINOTECAN RELATED COMPOUND B

Common Name

English

IT-141

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

840021

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

FDA ORPHAN DRUG

513715

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

Code System Code Type Description

CAS

86639-52-3

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

PUBCHEM

104842

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

FDA UNII

0H43101T0J

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

EVMPD

SUB188424

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

NCI_THESAURUS

C61618

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

RS_ITEM_NUM

1347631

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

DRUG BANK

DB05482

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

SMS_ID

100000174485

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

CHEBI

8988

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

WIKIPEDIA

SN-38

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

EPA CompTox

DTXSID4040399

Created by admin on Fri Dec 15 15:42:24 UTC 2023 , Edited by admin on Fri Dec 15 15:42:24 UTC 2023

PRIMARY

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7-ETHYL-10-HYDROXYCAMPTOTHECIN

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				INTRAVENOUS ADMINISTRATION