SERDEXMETHYLPHENIDATE

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H29N3O8
Molecular Weight	499.5131
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SERDEXMETHYLPHENIDATE

Structure Search

SMILES

[H][C@@]1(CCCCN1C(=O)OC[N+]2=CC=CC(=C2)C(=O)N[C@@H](CO)C([O-])=O)[C@H](C(=O)OC)C3=CC=CC=C3

InChI

InChIKey=UBZPNQRBUOBBLN-PWRODBHTSA-N

InChI=1S/C25H29N3O8/c1-35-24(33)21(17-8-3-2-4-9-17)20-11-5-6-13-28(20)25(34)36-16-27-12-7-10-18(14-27)22(30)26-19(15-29)23(31)32/h2-4,7-10,12,14,19-21,29H,5-6,11,13,15-16H2,1H3,(H-,26,30,31,32)/t19-,20+,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C25H29N3O8
Molecular Weight	499.5131
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 13:40:47 UTC 2023` Edited by `admin` on `Sat Dec 16 13:40:47 UTC 2023`
Record UNII	0H8KZ470DW
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SERDEXMETHYLPHENIDATE

Official Name

English

KP-415 INNER SALT

Code

English

serdexmethylphenidate [INN]

Common Name

English

SERDEXMETHYLPHENIDATE [USAN]

Common Name

English

N-(1-((((2R)-2-((1R)-2-METHOXY-2-OXO-1-PHENYLETHYL)PIPERIDINE-1-CARBONYL)OXY)METHYL)PYRIDIN-1-IUM-3-CARBONYL)-L-SERINATE

Systematic Name

English

Serdexmethylphenidate [WHO-DD]

Common Name

English

PYRIDINIUM, 3-((((1S)-1-CARBOXY-2-HYDROXYETHYL)AMINO)CARBONYL)-1-(((((2R)-2-((1R)-2-METHOXY-2-OXO-1-PHENYLETHYL)-1-PIPERIDINYL)CARBONYL)OXY)METHYL)-

Systematic Name

English

Classification Tree Code System Code

DEA NO.

1729

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

FDA ORPHAN DRUG

878522

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

Code System Code Type Description

CAS

2014450-84-9

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

ALTERNATIVE

SMS_ID

300000005913

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

CAS

1996626-29-9

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

FDA UNII

0H8KZ470DW

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

RXCUI

2562176

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

INN

10916

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

PUBCHEM

134823895

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

NCI_THESAURUS

C166420

Created by admin on Sat Dec 16 13:40:47 UTC 2023 , Edited by admin on Sat Dec 16 13:40:47 UTC 2023

PRIMARY

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SERDEXMETHYLPHENIDATE

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


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SERDEXMETHYLPHENIDATE CHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					0H8KZ470DW

SERDEXMETHYLPHENIDATE

EXCRETED UNCHANGED

Qualification:

FECAL

Amount:


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PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Amount:

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DEXMETHYLPHENIDATE

METABOLITE ACTIVE -> PRODRUG

Amount:

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DEXMETHYLPHENIDATE

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC		`0H8KZ470DW` SERDEXMETHYLPHENIDATE		FASTED STATE PHARMACOKINETIC SINGLE DOSE ADMINISTRATION PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC		`0H8KZ470DW` SERDEXMETHYLPHENIDATE		IN HEALTHY ADULT SUBJECTS PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC		`0H8KZ470DW` SERDEXMETHYLPHENIDATE		after AZSTARYS administration PHARMACOKINETIC