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Details

Stereochemistry RACEMIC
Molecular Formula C16H14F3N3O2S
Molecular Weight 369.361
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LANSOPRAZOLE

SMILES

CC1=C(C[S+]([O-])C2=NC3=C(N2)C=CC=C3)N=CC=C1OCC(F)(F)F

InChI

InChIKey=MJIHNNLFOKEZEW-UHFFFAOYSA-N
InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)

HIDE SMILES / InChI
Molecular Formula C16H14F3N3O2S
Molecular Weight 369.361
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:37:11 UTC 2023
Edited
by admin
on Fri Dec 15 15:37:11 UTC 2023
Record UNII
0K5C5T2QPG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LANSOPRAZOLE
EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
LANSOPRAZOLE [MI]
Common Name English
LANZOR
Brand Name English
AG-1749
Code English
LANSOPRAZOLE [ORANGE BOOK]
Common Name English
2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole
Systematic Name English
LANSOPRAZOLE COMPONENT OF PREVPAC
Common Name English
LANSOPRAZOLE [USP MONOGRAPH]
Common Name English
PREVACID
Brand Name English
PREVPAC COMPONENT LANSOPRAZOLE
Brand Name English
TAKEPRON
Brand Name English
2-(((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE
Systematic Name English
Lansoprazole [WHO-DD]
Common Name English
A-65006
Code English
LANSOPRAZOLE [EP MONOGRAPH]
Common Name English
LANZOPRAZOLE
Common Name English
AGOPTON
Brand Name English
lansoprazole [INN]
Common Name English
(±)-LANSOPRAZOLE
Common Name English
PREVONCO
Brand Name English
NSC-758638
Code English
LANSOX
Brand Name English
LANSOPRAZOLE [USP-RS]
Common Name English
LIMPIDEX
Brand Name English
LANSOPRAZOLE [HSDB]
Common Name English
LANSOPRAZOLE [JAN]
Common Name English
LANSOPRAZOLE [MART.]
Common Name English
1H-BENZIMIDAZOLE, 2-(((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)-
Systematic Name English
OGAST
Brand Name English
ZOTON
Brand Name English
OGASTORO
Brand Name English
LANSOPRAZOLE [VANDF]
Common Name English
LANSOPRAZOLE [USAN]
Common Name English
Classification Tree Code System Code
WHO-ATC A02BC03
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-VATC QA02BD07
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
LIVERTOX NBK548452
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-VATC QA02BD03
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BD03
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-VATC QA02BD02
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BD02
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BD10
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BD07
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
NCI_THESAURUS C29723
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-VATC QA02BC03
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
FDA ORPHAN DRUG 446014
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BC53
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
NDF-RT N0000000147
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
NDF-RT N0000175525
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
FDA ORPHAN DRUG 264508
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
WHO-ATC A02BD09
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
Code System Code Type Description
MERCK INDEX
m6683
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY Merck Index
DAILYMED
0K5C5T2QPG
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
SMS_ID
100000089867
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
RXCUI
17128
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY RxNorm
RS_ITEM_NUM
1356916
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
NDF-RT
N0000009724
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY Inhibition Gastric Acid Secretion [PE]
PUBCHEM
3883
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
DRUG CENTRAL
1547
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
CAS
103577-45-3
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
INN
6397
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
IUPHAR
7208
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
DRUG BANK
DB00448
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
NCI_THESAURUS
C29150
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
WIKIPEDIA
LANSOPRAZOLE
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
MESH
C058687
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
NSC
758638
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
HSDB
7204
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
LACTMED
Lansoprazole
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
EPA CompTox
DTXSID4023200
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
FDA UNII
0K5C5T2QPG
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
EVMPD
SUB08403MIG
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
ChEMBL
CHEMBL480
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
USAN
AA-78
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
CHEBI
6375
Created by admin on Fri Dec 15 15:37:11 UTC 2023 , Edited by admin on Fri Dec 15 15:37:11 UTC 2023
PRIMARY
Related Record Type Details
Structure of DEXLANSOPRAZOLE
ENANTIOMER -> RACEMATE
Structure of LANSOPRAZOLE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
CYTOCHROME P450 2C19
METABOLIC ENZYME -> SUBSTRATE
Structure of LANSOPRAZOLE N-OXIDE
DEGRADENT -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
Structure of LANSOPRAZOLE SODIUM
SALT/SOLVATE -> PARENT
CYTOCHROME P450 1A2
METABOLIC ENZYME -> INDUCER
Structure of LEVOLANSOPRAZOLE
ENANTIOMER -> RACEMATE
Structure of LANSOPRAZOLE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1
TARGET -> INHIBITOR
Structure of LANSOPRAZOLE N-OXIDE
DEGRADENT -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of AG-2000 FREE BASE
METABOLITE ACTIVE -> PRODRUG
Structure of 2-(2-HYDROXYSULFANYL-3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-1-IUM-1-YL)-1H-BENZIMIDAZOLE
METABOLITE ACTIVE -> PRODRUG
Structure of AG-1812 FREE BASE
METABOLITE ACTIVE -> PRODRUG
Structure of 5-HYDROXYLANSOPRAZOLE
METABOLITE -> PARENT
These metabolites have very little or no antisecretory activity.
Structure of LANSOPRAZOLE SULFONE
METABOLITE -> PARENT
Related Record Type Details
Structure of LANSOPRAZOLE SULFIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of LANSOPRAZOLE SULFIDE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of LANSOPRAZOLE N-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2-BENZIMIDAZOLINONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-BENZIMIDAZOLETHIOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of LANSOPRAZOLE N-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of LANSOPRAZOLE SULFONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 2-(((4-CHLORO-3-METHYLPYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE, (±)-
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of LANSOPRAZOLE SULFONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC With Hepatic impairment
PHARMACOKINETIC
Elderly
PHARMACOKINETIC
NIH
NCATS
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