AMINOGLUTETHIMIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H16N2O2
Molecular Weight	232.2783
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AMINOGLUTETHIMIDE

Structure Search

SMILES

CCC1(CCC(=O)NC1=O)C2=CC=C(N)C=C2

InChI

InChIKey=ROBVIMPUHSLWNV-UHFFFAOYSA-N

InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C13H16N2O2
Molecular Weight	232.2783
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:04:58 UTC 2023` Edited by `admin` on `Fri Dec 15 15:04:58 UTC 2023`
Record UNII	0O54ZQ14I9
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMINOGLUTETHIMIDE

Official Name

English

2,6-PIPERIDINEDIONE, 3-(4-AMINOPHENYL)-3-ETHYL-

Systematic Name

English

AMINOGLUTETHIMIDE [MI]

Common Name

English

NSC-330915

Code

English

CYTADREN

Brand Name

English

AMINOGLUTETHIMIDE [USP IMPURITY]

Common Name

English

aminoglutethimide [INN]

Common Name

English

AMINOGLUTETHIMIDE [EP MONOGRAPH]

Common Name

English

2-(P-AMINOPHENYL)-2-ETHYLGLUTARIMIDE

Common Name

English

AMINOGLUTETHIMIDE [ORANGE BOOK]

Common Name

English

AMINOGLUTETHIMIDE [MART.]

Common Name

English

AMINOGLUTETHIMIDE [EP IMPURITY]

Common Name

English

AMINOGLUTETHIMIDE [VANDF]

Common Name

English

AMINOGLUTETHIMIDE [HSDB]

Common Name

English

Aminoglutethimide [WHO-DD]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175921

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

NCI_THESAURUS

C2355

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

LIVERTOX

40

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

NCI_THESAURUS

C2018

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

NDF-RT

N0000175928

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

WHO-VATC

QL02BG01

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

WHO-ATC

L02BG01

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

Code System Code Type Description

DRUG CENTRAL

164

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

NCI_THESAURUS

C233

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

RXCUI

677

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

RxNorm

FDA UNII

0O54ZQ14I9

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

NSC

330915

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

CHEBI

2654

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

HSDB

7494

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

PUBCHEM

2145

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

ChEMBL

CHEMBL488

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

MERCK INDEX

m1707

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

Merck Index

EVMPD

SUB05440MIG

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

EPA CompTox

DTXSID8022589

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

IUPHAR

7054

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

WIKIPEDIA

AMINOGLUTETHIMIDE

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

DRUG BANK

DB00357

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

ECHA (EC/EINECS)

204-756-4

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

INN

837

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

MESH

D000616

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

SMS_ID

100000092761

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

CAS

125-84-8

Created by admin on Fri Dec 15 15:04:58 UTC 2023 , Edited by admin on Fri Dec 15 15:04:58 UTC 2023

PRIMARY

Related Record Type Details


					5S1T2OED7F

AMINOGLUTETHIMIDE, (S)-

ENANTIOMER -> RACEMATE


					LUC985IS6T

AMINOGLUTETHIMIDE, (R)-

ENANTIOMER -> RACEMATE


					0O54ZQ14I9

AMINOGLUTETHIMIDE

EXCRETED UNCHANGED

Comments:

After ingestion of a single oral dose, 34%-54% is excreted in the urine as unchanged drug during the first 48 hours

Qualification:

URINE

Amount:

Related Record Type Details


					2V4Z73WCN5

P-AMINO-1'-HYDROXYGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					KWY4CM2XCR

3-(4-AMINOPHENYL)TETRAHYDRO-2-OXO-3-FURANPROPANAMIDE

METABOLITE -> PARENT

Qualification:

URINE


					NBU7BB9E4C

P-ACETYLAMINO-5-HYDROXYGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					1JJG4JG4I8

P-NITROGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					CRS26MT9JA

FORMYLAMINOGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					AW5WG92FW9

HYDROXYAMINOGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					SSL5GR3QU4

ACETYLAMINOGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE


					VNQ625J47F

P-AMINO-5-HYDROXYGLUTETHIMIDE

METABOLITE -> PARENT

Qualification:

URINE

Related Record Type Details


					WWE01RI3RA

M-NITROGLUTETHIMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					QX04QC4IHW

3-AMINOGLUTETHIMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					1JJG4JG4I8

P-NITROGLUTETHIMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					0O54ZQ14I9

AMINOGLUTETHIMIDE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				ORAL ADMINISTRATION

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION