TOLRESTAT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14F3NO3S
Molecular Weight	357.347
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TOLRESTAT

Structure Search

SMILES

COC1=C(C2=C(C=C1)C(=CC=C2)C(=S)N(C)CC(O)=O)C(F)(F)F

InChI

InChIKey=LUBHDINQXIHVLS-UHFFFAOYSA-N

InChI=1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)

HIDE SMILES / InChI

Molecular Formula	C16H14F3NO3S
Molecular Weight	357.347
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:55:11 UTC 2023` Edited by `admin` on `Fri Dec 15 18:55:11 UTC 2023`
Record UNII	0T93LG5NMK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TOLRESTAT

Official Name

English

Tolrestat [WHO-DD]

Common Name

English

tolrestat [INN]

Common Name

English

TOLRESTAT [MART.]

Common Name

English

TOLRESTAT [MI]

Common Name

English

AY-27,773

Code

English

TOLRESTAT [USAN]

Common Name

English

N-[6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl]sarcosine

Systematic Name

English

ALREDASE

Brand Name

English

AY-27773

Code

English

GLYCINE, N-((6-METHOXY-5-(TRIFLUOROMETHYL)-1-NAPHTHALENYL)THIOXOMETHYL)-N-METHYL-

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QA10XA01

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

NCI_THESAURUS

C72880

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

WHO-ATC

A10XA01

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

Code System Code Type Description

INN

5529

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

CAS

82964-04-3

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

MESH

C040550

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

NCI_THESAURUS

C96310

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

SMS_ID

100000077766

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

RXCUI

38386

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

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RxNorm

USAN

U-19

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

IUPHAR

7404

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

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DRUG BANK

DB02383

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

CHEBI

48549

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

EPA CompTox

DTXSID80904890

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

ChEMBL

CHEMBL436

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

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DRUG CENTRAL

2704

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

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WIKIPEDIA

Tolrestat

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

MERCK INDEX

m10953

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

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Merck Index

PUBCHEM

53359

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

FDA UNII

0T93LG5NMK

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

EVMPD

SUB11179MIG

Created by admin on Fri Dec 15 18:55:11 UTC 2023 , Edited by admin on Fri Dec 15 18:55:11 UTC 2023

PRIMARY

Related Record Type Details


					73C27N6Z7U

ALDOSE REDUCTASE

TARGET -> INHIBITOR

Comments:

https://en.wikipedia.org/wiki/Tolrestat

Related Record Type Details


					0T93LG5NMK

TOLRESTAT

ACTIVE MOIETY