INCB-3284

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H31F3N4O4
Molecular Weight	520.5439
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=NC=C(C=C1)[C@]2(O)CC[C@@H](CC2)N3CC[C@H](C3)NC(=O)CNC(=O)C4=CC(=CC=C4)C(F)(F)F

InChI

InChIKey=NXZNYBUBXWWKCP-DNRQZRRGSA-N

InChI=1S/C26H31F3N4O4/c1-37-23-6-5-19(14-30-23)25(36)10-7-21(8-11-25)33-12-9-20(16-33)32-22(34)15-31-24(35)17-3-2-4-18(13-17)26(27,28)29/h2-6,13-14,20-21,36H,7-12,15-16H2,1H3,(H,31,35)(H,32,34)/t20-,21-,25-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H31F3N4O4
Molecular Weight	520.5439
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:54:35 UTC 2023` Edited by `admin` on `Sat Dec 16 10:54:35 UTC 2023`
Record UNII	0W6K09GAQB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

INCB-3284

Code

English

BENZAMIDE, N-(2-(((3R)-1-(TRANS-4-HYDROXY-4-(6-METHOXY-3-PYRIDINYL)CYCLOHEXYL)-3-PYRROLIDINYL)AMINO)-2-OXOETHYL)-3-(TRIFLUOROMETHYL)-

Systematic Name

English

INCB3284

Code

English

INCB003284

Code

English

INCB-003284

Code

English

Code System Code Type Description

CAS

887401-92-5

Created by admin on Sat Dec 16 10:54:36 UTC 2023 , Edited by admin on Sat Dec 16 10:54:36 UTC 2023

PRIMARY

DRUG BANK

DB05130

Created by admin on Sat Dec 16 10:54:36 UTC 2023 , Edited by admin on Sat Dec 16 10:54:36 UTC 2023

PRIMARY

PUBCHEM

11527661

Created by admin on Sat Dec 16 10:54:36 UTC 2023 , Edited by admin on Sat Dec 16 10:54:36 UTC 2023

PRIMARY

FDA UNII

0W6K09GAQB

Created by admin on Sat Dec 16 10:54:36 UTC 2023 , Edited by admin on Sat Dec 16 10:54:36 UTC 2023

PRIMARY

Related Record Type Details


					5XA76PCG9F

C-C CHEMOKINE RECEPTOR TYPE 2

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					5XA76PCG9F

C-C CHEMOKINE RECEPTOR TYPE 2

TARGET -> INHIBITOR

Comments:

Antagonism of chemotaxis activity

Qualification:

IC50

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					5ET5U3KG6K

INCB-3284 DIMESYLATE

SALT/SOLVATE -> PARENT

Amount:


					SEV29N8JND

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2

OFF-TARGET->INHIBITOR

Amount:

Related Record Type Details


					0W6K09GAQB

INCB-3284

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC