METRONIDAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H9N3O3
Molecular Weight	171.154
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METRONIDAZOLE

Structure Search

SMILES

CC1=NC=C(N1CCO)[N+]([O-])=O

InChI

InChIKey=VAOCPAMSLUNLGC-UHFFFAOYSA-N

InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

HIDE SMILES / InChI

Molecular Formula	C6H9N3O3
Molecular Weight	171.154
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:19 UTC 2023` Edited by `admin` on `Fri Dec 15 15:11:19 UTC 2023`
Record UNII	140QMO216E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

METRONIDAZOLE

Official Name

English

METRONIDAZOLE COMPONENT OF HELIDAC

Common Name

English

METRONIDAZOLE [WHO-IP]

Common Name

English

VANDAZOLE

Brand Name

English

METRONIDAZOLE BENZOATE IMPURITY A [EP IMPURITY]

Common Name

English

METROMIDOL

Brand Name

English

FLAGYL

Brand Name

English

NSC-50364

Code

English

METRONIDAZOLE COMPONENT OF PYLERA

Common Name

English

BAYER 5360

Code

English

METRONIDAZOLE [IARC]

Common Name

English

Metronidazole [WHO-DD]

Common Name

English

METRONIDAZOLE [USAN]

Common Name

English

PYLERA COMPONENT METRONIDAZOLE

Common Name

English

METROGEL

Brand Name

English

METRONIDAZOLE [USP IMPURITY]

Common Name

English

METRONIDAZOLE [MI]

Common Name

English

DEFLAMON

Common Name

English

METRONIDAZOLE [HSDB]

Common Name

English

METRONIDAZOLE [EP MONOGRAPH]

Common Name

English

SATRIC

Brand Name

English

2-Methyl-5-nitroimidazole-1-ethanol

Systematic Name

English

HELIDAC COMPONENT METRONIDAZOLE

Common Name

English

metronidazole [INN]

Common Name

English

RP 8823

Code

English

METRONIDAZOLE [VANDF]

Common Name

English

RP-8823

Code

English

METRONIDAZOLE [USP-RS]

Common Name

English

METRO I.V.

Brand Name

English

BAYER-5360

Code

English

PROTOSTAT

Brand Name

English

METRONIDAZOLE [ORANGE BOOK]

Common Name

English

METRONIDAZOLE [JAN]

Common Name

English

ORVAGIL

Common Name

English

METRONIDAZOLE [EP IMPURITY]

Common Name

English

NORITATE

Brand Name

English

METROLOTION

Brand Name

English

METROCREAM

Brand Name

English

METROGEL-VAGINAL

Brand Name

English

GINEFLAVIR

Common Name

English

METRONIDAZOLE [USP MONOGRAPH]

Common Name

English

ZADSTAT

Common Name

English

METRONIDAZOLE [MART.]

Common Name

English

NSC-69587

Code

English

LIKMEZ

Brand Name

English

Classification Tree Code System Code

WHO-ESSENTIAL MEDICINES LIST

6.5.1

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QA02BD02

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

NDF-RT

N0000175435

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.2

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

P01AB01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QG01AF01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

J01XD01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A02BD01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

J01RA10

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

G01AF01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A02BD03

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

D06BX01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A02BD11

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

J01RA04

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

LIVERTOX

NBK548609

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

CFR

21 CFR 530.41

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

17486

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QP51AA01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QA02BD03

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

NCI_THESAURUS

C279

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

EU-Orphan Drug

EU/3/11/875

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

267008

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

EPA PESTICIDE CODE

120401

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

P01AB51

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A02BD02

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

339111

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

J01RA03

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A02BD08

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QD06BX01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

247907

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

21687

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QJ01XD01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

514715

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

NDF-RT

N0000007663

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QA01AB17

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

FDA ORPHAN DRUG

61891

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QA02BD08

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

NDF-RT

N0000007663

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-VATC

QA02BD01

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

WHO-ATC

A01AB17

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

Code System Code Type Description

SMS_ID

100000090285

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

ECHA (EC/EINECS)

207-136-1

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

PUBCHEM

4173

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

INN

1032

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

CAS

443-48-1

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

NCI_THESAURUS

C651

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

EPA CompTox

DTXSID2020892

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

NSC

69587

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

LACTMED

Metronidazole

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

RS_ITEM_NUM

1442009

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

CHEBI

6909

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

MESH

D008795

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

METRONIDAZOLE

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

Description: A white or pale yellow, crystalline powder; odourless or almost odourless.Solubility: Sparingly soluble in water; slightly soluble in ethanol (~750 g/l) TS and ether R.Category: Antitrichomonal; antiamoebic. Storage: Metronidazole should be kept in a well-closed container, protected from light. Additional information: Metronidazole is stable in air, but darkens on exposure to light. Definition: Metronidazole contains not less than 99.0% and not more than 101.0% of C6H9N3O3, calculated with reference to the dried substance.

CHEBI

50687

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

DRUG CENTRAL

1790

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

EVMPD

SUB08922MIG

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

ChEMBL

CHEMBL137

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

RXCUI

6922

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

RxNorm

NSC

50364

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

FDA UNII

140QMO216E

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

HSDB

3129

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

DAILYMED

140QMO216E

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

MERCK INDEX

m7506

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

METRONIDAZOLE

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

DRUG BANK

DB00916

Created by admin on Fri Dec 15 15:11:19 UTC 2023 , Edited by admin on Fri Dec 15 15:11:19 UTC 2023

PRIMARY

Related Record Type Details


					76JC1633UF

METRONIDAZOLE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

POTENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					8Y356BW999

metronidazole citrate

PRODRUG -> METABOLITE ACTIVE

Amount:


					7RUI9488IL

1-(2-HYDROXYETHYL)-2-(HYDROXYMETHYL)-5-NITROIMIDAZOLE

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					69IKL472BQ

2-METHYL-5-NITROIMIDAZOL-1-YLACETIC ACID

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					2Y6DYT8UW8

METRONIDAZOLE GLUCURONIDE

METABOLITE -> PARENT

Amount:

Related Record Type Details


					0WI2PRW4QM

2-(2-METHYL-4-NITRO-1H-IMIDAZOL-1-YL)ETHANOL

IMPURITY -> PARENT


					UD15593HGR

2-(4-NITRO-1H-IMIDAZOL-1-YL)ETHANOL

IMPURITY -> PARENT


					69IKL472BQ

2-METHYL-5-NITROIMIDAZOL-1-YLACETIC ACID

IMPURITY -> PARENT


					Q0SET9S9CB

2-(2-(2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHOXY)ETHOXY)ETHANOL

IMPURITY -> PARENT


					1EJE896YYV

2-(2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHOXY)ETHANOL

IMPURITY -> PARENT


					7RUI9488IL

1-(2-HYDROXYETHYL)-2-(HYDROXYMETHYL)-5-NITROIMIDAZOLE

IMPURITY -> PARENT


					Z31100A55O

1-METHYL-4-NITRO-1H-IMIDAZOLE

IMPURITY -> PARENT


					M69F775144

2-(5-NITRO-1H-IMIDAZOL-1-YL)ETHANOL

IMPURITY -> PARENT


					1EJE896YYV

2-(2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHOXY)ETHANOL

IMPURITY -> PARENT


					A355C835XC

METRONIDAZOLE BENZOATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Y8U32AZ5O7

4-NITROIMIDAZOLE

IMPURITY -> PARENT

Related Record Type Details


					140QMO216E

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				POPULATION: CHILDREN AND ADOLESCENTS

MIC	BIOLOGICAL				PATHOGEN: ANAEROBES SUSCEPTIBILITY: INTERMEDIATE

Tmax	PHARMACOKINETIC				FORMULATION: IMMEDIATE RELEASE

MIC	BIOLOGICAL				PATHOGEN: ANAEROBES SUSCEPTIBILITY: RESISTANT

Biological Half-life	PHARMACOKINETIC				POPULATION: ADULTS

Biological Half-life	PHARMACOKINETIC				POPULATION: NEONATES 7 DAYS AND OLDER

Biological Half-life	PHARMACOKINETIC				CHILD-PUGH CLASSIFICATION: CLASS A

MIC	BIOLOGICAL				PATHOGEN: ANAEROBES SUSCEPTIBILITY: SUSCEPTIBLE

Biological Half-life	PHARMACOKINETIC				POPULATION: NEONATES GESTATIONAL AGE 36-40 WEEKS

Biological Half-life	PHARMACOKINETIC				POPULATION: NEONATES GESTATIONAL AGE 32-35 WEEKS

Biological Half-life	PHARMACOKINETIC				CREATININE CLEARANCE: LESS THAN OR EQUAL TO 65 ML/MIN RENAL FUNCTION: IMPAIRED

Tmax	PHARMACOKINETIC				FORMULATION: EXTENDED RELEASE

Biological Half-life	PHARMACOKINETIC				CHILD-PUGH CLASSIFICATION: CLASS C

Biological Half-life	PHARMACOKINETIC				CHILD-PUGH CLASSIFICATION: CLASS B

Biological Half-life	PHARMACOKINETIC				POPULATION: NEONATES GESTATIONAL AGE 28-30 WEEKS