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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H30O2
Molecular Weight 314.4617
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CANNABIDIOL

SMILES

CCCCCC1=CC(O)=C([C@@H]2C=C(C)CC[C@H]2C(C)=C)C(O)=C1

InChI

InChIKey=QHMBSVQNZZTUGM-ZWKOTPCHSA-N
InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

HIDE SMILES / InChI
Molecular Formula C21H30O2
Molecular Weight 314.4617
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:30:49 UTC 2023
Edited
by admin
on Sat Dec 16 16:30:49 UTC 2023
Record UNII
19GBJ60SN5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CANNABIDIOL
INCI   INN   MART.   MI   USAN   WHO-DD  
USAN   INN   INCI  
Official Name English
CANNABIDIOL [USAN]
Common Name English
CANNABIDIOL [USP-RS]
Common Name English
.DELTA.1(2)-TRANS-CANNABIDIOL
Common Name English
Cannabidiol [WHO-DD]
Common Name English
(-)-CANNABIDIOL
Common Name English
EPIDIOLEX
Brand Name English
CANNABIDIOL [MART.]
Common Name English
CARDIOLRX
Brand Name English
2-((1R,6R)-3-METHYL-6-(PROP-1-EN-2-YL)CYCLOHEX-2-EN-1-YL)-5-PENTYLBENZENE-1,3-DIOL
Systematic Name English
2-((1R,6R)-3-METHYL-6-(1-METHYLETHENYL)CYCLOHEX-2-ENYL)-5-PENTYLBENZENE-1,3-DIOL
Systematic Name English
CANNABIDIOL [INCI]
Common Name English
BTX-1503
Code English
(-)-CBD
Common Name English
GWP-42003
Code English
CANNABIDIOL [MI]
Common Name English
CBD
Common Name English
BTX-1204
Code English
CANNABIDIOL [ORANGE BOOK]
Common Name English
1,3-BENZENEDIOL, 2-((1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL)-5-PENTYL-
Systematic Name English
CANNABIDIOL SOLUTION [USP-RS]
Common Name English
GWP-42003-P
Code English
cannabidiol [INN]
Common Name English
GWP42003
Code English
(-)-TRANS-CANNABIDIOL
Common Name English
GWP42003-P
Code English
Classification Tree Code System Code
EU-Orphan Drug EU/3/17/1959
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 471815
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 510716
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
NCI_THESAURUS C274
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 914322
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
NCI_THESAURUS C1742
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 444814
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 409313
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 860921
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 609617
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
DSLD 3397 (Number of products:162)
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 617417
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 521416
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
WHO-ATC N03AX24
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 452614
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 620417
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 696519
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 734820
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 806620
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 545316
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 482315
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 656618
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 736020
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 439414
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 819221
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 538916
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
WHO-ATC N02BG10
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 763820
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 486115
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 610117
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 488315
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 421213
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 628818
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 549616
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 498215
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 438214
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 668918
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 734620
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 860821
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
FDA ORPHAN DRUG 450814
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
NCI_THESAURUS C105578
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
Code System Code Type Description
RXCUI
2045371
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
RS_ITEM_NUM
1089149
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
ChEMBL
CHEMBL190461
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
LACTMED
Cannabidiol
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
USAN
CD-48
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
EVMPD
SUB26600
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
NCI_THESAURUS
C118452
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
WIKIPEDIA
CANNABIDIOL
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
CHEBI
69478
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
RS_ITEM_NUM
1089161
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
ALTERNATIVE
INN
10423
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
DRUG BANK
DB09061
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
DAILYMED
19GBJ60SN5
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
DRUG CENTRAL
5288
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
FDA UNII
19GBJ60SN5
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
CAS
13956-29-1
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
PUBCHEM
644019
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
EPA CompTox
DTXSID00871959
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
SMS_ID
100000091179
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
MESH
D002185
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY
MERCK INDEX
m3020
Created by admin on Sat Dec 16 16:30:52 UTC 2023 , Edited by admin on Sat Dec 16 16:30:52 UTC 2023
PRIMARY Merck Index
Related Record Type Details
CANNABINOID RECEPTOR 1
TARGET->INVERSE AGONIST
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A7
METABOLIC ENZYME -> SUBSTRATE
CANNABIS SATIVA SUBSP. INDICA TOP
PARENT -> ACTIVE CONSTITUENT ALWAYS PRESENT
Cannabidiol Class | Anxiolytic Antipsychotic | Analgesic | Anti-inflammatory | Antioxydant | Antispasmodic
G-PROTEIN COUPLED RECEPTOR 55
TARGET -> INHIBITOR
5-HYDROXYTRYPTAMINE RECEPTOR 1A
TARGET -> ACTIVATOR
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9
METABOLIC ENZYME -> SUBSTRATE
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
CYTOCHROME P450 2C9
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 2C19
METABOLIC ENZYME -> INHIBITOR
Responsible for a drug interaction with clobazam. Mean increase in clozabam and N-desmethylclozabam levels was 60% and 500%, respectively, after 4 weeks of concomitant therapy.
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 2C19
METABOLIC ENZYME -> SUBSTRATE
CANNABINOID RECEPTOR 2
TARGET->INVERSE AGONIST
Related Record Type Details
Structure of 2''-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MINOR
Structure of 7-CARBOXYCANNABIDIOL
METABOLITE INACTIVE -> PARENT
The major circulating metabolites include 7-carboxy-cannabidiol (7-COOH-CBD), which was approximately 40-fold higher than the parent.
MAJOR
Structure of 6ALPHA-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MAJOR
Structure of 5''-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MINOR
Structure of 3''-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MINOR
Structure of CANNABIDIOL DIMETHYL ETHER
METABOLITE -> PARENT
Structure of 1''-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MINOR
Structure of 7-HYDROXYCANNABIDIOL
METABOLITE ACTIVE -> PARENT
The major circulating metabolites include 7-hydroxy-cannabidiol (7-OH-CBD), which was approximately 38% of the parent based on AUC of cannabidiol.
MAJOR
Structure of 4''-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MINOR
Structure of 6.BETA.-HYDROXYCANNABIDIOL
METABOLITE -> PARENT
MAJOR
Related Record Type Details
Structure of CANNABIDIOL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC TWICE-DAILY DOSING FOR 7 DAYS

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