CLEVIDIPINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H23Cl2NO6
Molecular Weight	456.316
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLEVIDIPINE

Structure Search

SMILES

CCCC(=O)OCOC(=O)C1=C(C)NC(C)=C(C1C2=C(Cl)C(Cl)=CC=C2)C(=O)OC

InChI

InChIKey=KPBZROQVTHLCDU-UHFFFAOYSA-N

InChI=1S/C21H23Cl2NO6/c1-5-7-15(25)29-10-30-21(27)17-12(3)24-11(2)16(20(26)28-4)18(17)13-8-6-9-14(22)19(13)23/h6,8-9,18,24H,5,7,10H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C21H23Cl2NO6
Molecular Weight	456.316
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:11:33 UTC 2023` Edited by `admin` on `Sat Dec 16 17:11:33 UTC 2023`
Record UNII	19O2GP3B7Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLEVIDIPINE

Official Name

English

CLEVIDEPINE BUTYRATE [VANDF]

Common Name

English

Clevidipine [WHO-DD]

Common Name

English

CLEVIDIPINE [MI]

Common Name

English

CLEVIDIPINE [ORANGE BOOK]

Common Name

English

3,5-PYRIDINEDICARBOXYLIC ACID, 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-, 3-METHYL 5-((1-OXOBUTOXY)METHYL) ESTER

Common Name

English

CLEVIDEPINE

Common Name

English

CLEVIDIPINE [VANDF]

Common Name

English

CLEVIDEPINE BUTYRATE

Common Name

English

(Butanoyloxy)methyl methyl (4RS)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Systematic Name

English

CLEVIDIPINE BUTYRATE [VANDF]

Common Name

English

H-324/38

Code

English

CLEVIDIPINE [USAN]

Common Name

English

CLEVIDIPINE [MART.]

Common Name

English

CLEVIDIPINE BUTYRATE [ORANGE BOOK]

Common Name

English

H324/38

Code

English

CLEVIPREX

Brand Name

English

CLEVIDIPINE BUTYRATE

Common Name

English

CLEVIDEPINE [VANDF]

Common Name

English

clevidipine [INN]

Common Name

English

3,5-PYRIDINEDICARBOXYLIC ACID, 4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-, METHYL (1-OXOBUTOXY)METHYL ESTER

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000007556

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

WHO-ATC

C08CA16

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

NDF-RT

N0000175421

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

NDF-RT

N0000000069

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

NCI_THESAURUS

C333

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

WHO-VATC

QC08CA16

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

Code System Code Type Description

CAS

166432-28-6

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

SUPERSEDED

IUPHAR

7468

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

DRUG BANK

DB04920

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

INN

7490

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

ChEMBL

CHEMBL1237132

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

NCI_THESAURUS

C72727

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

EVMPD

SUB06655MIG

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

EPA CompTox

DTXSID6057661

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

RXCUI

977863

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

FDA UNII

19O2GP3B7Q

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

PUBCHEM

153994

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

DRUG CENTRAL

674

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

USAN

SS-88

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

SMS_ID

100000080215

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

WIKIPEDIA

Clevidipine

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

DAILYMED

19O2GP3B7Q

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

RXCUI

233603

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

ALTERNATIVE

MESH

C118563

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

CAS

167221-71-8

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

MERCK INDEX

m3620

Created by admin on Sat Dec 16 17:11:34 UTC 2023 , Edited by admin on Sat Dec 16 17:11:34 UTC 2023

PRIMARY

Merck Index

Related Record Type Details


					7405T4734R

CLEVIDIPINE, (S)-

ENANTIOMER -> RACEMATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					FT28P863D1

CLEVIDIPINE, (R)-

ENANTIOMER -> RACEMATE


					19O2GP3B7Q

EXCRETED UNCHANGED

Comments:

No intact parent compound is recovered in urine or feces, suggesting that clevidipine is completely and rapidly metabolized.

Qualification:

FECAL; URINE

Amount:


					OIC6NC9Q3P

VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D

TARGET -> INHIBITOR

Related Record Type Details


					446669RI9H

H-152/81

METABOLITE -> PARENT

Interaction Type:

MAJOR

Related Record Type Details


					19O2GP3B7Q

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC