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Details

Stereochemistry ABSOLUTE
Molecular Formula C62H86N12O16
Molecular Weight 1255.417
Optical Activity UNSPECIFIED
Defined Stereocenters 10 / 10
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DACTINOMYCIN

SMILES

[H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)C3=C4N=C5C(OC4=C(C)C=C3)=C(C)C(=O)C(N)=C5C(=O)N[C@H]6[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]7([H])CCCN7C(=O)[C@H](NC6=O)C(C)C)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C

InChI

InChIKey=RJURFGZVJUQBHK-IIXSONLDSA-N
InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1

HIDE SMILES / InChI
Molecular Formula C62H86N12O16
Molecular Weight 1255.417
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 10 / 10
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:14:37 UTC 2023
Edited
by admin
on Sat Dec 16 16:14:37 UTC 2023
Record UNII
1CC1JFE158
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DACTINOMYCIN
HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN   INN  
Official Name English
DACTINOMYCIN [HSDB]
Common Name English
ACTINOMYCIN C1
Common Name English
ACTINOMYCIN D [WHO-IP]
Common Name English
DACTINOMYCIN [WHO-IP]
Common Name English
3H-PHENOXAZINE-1,9-DICARBOXAMIDE, 2-AMINO-N,N'-BIS(HEXADECAHYDRO-6,13-DIISOPROPYL-2,5,9-TRIMETHYL-1,4,7,11,14-PENTAOXO-1H-PYRROLO(2,1-I)(1,4,7,10,13)OXATETRAAZACYCLOHEXADECIN-10-YL)-4,6-DIMETHYL-3-OXO-
Common Name English
ACTINOMYCIN-D
Common Name English
ACTINOMYCIN I1
Common Name English
DILACTONE ACTINOMYCIN D ACID
Common Name English
ACTINOMYCIN D [JAN]
Common Name English
DACTINOMYCIN [USP-RS]
Common Name English
GNF-PF-2290
Code English
DACTINOMYCIN [USP MONOGRAPH]
Common Name English
ACTINOMYCIN D [IARC]
Common Name English
DACTINOMYCIN [MART.]
Common Name English
DACTINOMYCIN [USAN]
Common Name English
DACTINOMYCIN [VANDF]
Common Name English
MERACTINOMYCIN
Common Name English
Dactinomycin [WHO-DD]
Common Name English
ACTINOMYCIN X1
Common Name English
DACTINOMYCINUM [WHO-IP LATIN]
Common Name English
DACTINOMYCIN [MI]
Common Name English
DACTINOMYCIN [ORANGE BOOK]
Common Name English
N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE) DILACTONE
Common Name English
NSC-3053
Code English
Actinomycin D
WHO-IP  
Common Name English
NCI-C04682
Code English
ACTINOMYCIN IV
Common Name English
dactinomycin [INN]
Common Name English
ONCOSTATIN K
Common Name English
COSMEGEN
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C204
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.2
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
NDF-RT N0000000233
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
LIVERTOX NBK548778
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
IARC Actinomycin D
NDF-RT N0000000150
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
NDF-RT N0000180850
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
WHO-ATC L01DA01
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
WHO-VATC QL01DA01
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
Code System Code Type Description
RS_ITEM_NUM
1162400
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
HSDB
3220
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
PUBCHEM
457193
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
DRUG BANK
DB00970
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
MERCK INDEX
m4067
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY Merck Index
LACTMED
Dactinomycin
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
EVMPD
SUB129914
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
CAS
50-76-0
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
FDA UNII
1CC1JFE158
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
NCI_THESAURUS
C412
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-063-6
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
EPA CompTox
DTXSID9020031
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
DAILYMED
1CC1JFE158
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
DACTINOMYCIN
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY Description: An orange-red to red, crystalline powder.Solubility: Soluble in water at 10 ?C and slightly soluble in water at 37 ?C; freely soluble in ethanol (~750 g/l) TS and methanol R;very slightly soluble in ether R.Category: Cytotoxic drug.Storage: Dactinomycin should be kept in a tightly closed container, protected from light, and stored at a temperature notexceeding 40 ?C.Additional information: Dactinomycin is hygroscopic and is affected by light and heat.CAUTION: Dactinomycin must be handled with care, avoiding contact with the skin and inhalation of airborne particles.
EVMPD
SUB13528MIG
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
CHEBI
27666
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
MESH
D003609
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
ChEMBL
CHEMBL1554
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
SMS_ID
100000085032
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
INN
1155
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
RXCUI
3100
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY RxNorm
WIKIPEDIA
Dactinomycin
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
DRUG CENTRAL
774
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
NSC
3053
Created by admin on Sat Dec 16 16:14:38 UTC 2023 , Edited by admin on Sat Dec 16 16:14:38 UTC 2023
PRIMARY
Related Record Type Details
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> SUBSTRATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of DACTINOMYCIN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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