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Details

Stereochemistry RACEMIC
Molecular Formula C20H25ClN2O5
Molecular Weight 408.876
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMLODIPINE

SMILES

CCOC(=O)C1=C(COCCN)NC(C)=C(C1C2=C(Cl)C=CC=C2)C(=O)OC

InChI

InChIKey=HTIQEAQVCYTUBX-UHFFFAOYSA-N
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C20H25ClN2O5
Molecular Weight 408.876
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:13:23 UTC 2023
Edited
by admin
on Fri Dec 15 17:13:23 UTC 2023
Record UNII
1J444QC288
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMLODIPINE
EMA EPAR   INN   MART.   MI   ORANGE BOOK   VANDF   WHO-DD  
INN  
Official Name English
AMLODIPINE [VANDF]
Common Name English
HGP-0904
Code English
Amlodipine [WHO-DD]
Common Name English
3-ETHYL 5-METHYL (±)-2-((2-AMINOETHOXY)METHYL)-4-(O-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLATE
Common Name English
3,5-PYRIDINEDICARBOXYLIC ACID, 2-((2-AMINOETHOXY)METHYL)-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-, 3-ETHYL 5-METHYL ESTER, (±)-
Common Name English
AMLODIPINE [MART.]
Common Name English
AMLODIPINE [ORANGE BOOK]
Common Name English
CKD-330 COMPONENT AMLODIPINE
Code English
HGP0904
Code English
AMLODIPINE [MI]
Common Name English
AMLODIPINE [EMA EPAR]
Common Name English
amlodipine [INN]
Common Name English
Classification Tree Code System Code
WHO-ATC C10BX14
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB05
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09XA53
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB04
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C10BX07
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09BB04
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC08CA01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
NCI_THESAURUS C333
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
NDF-RT N0000175421
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C10BX03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
LIVERTOX NBK548585
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09BB03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C08GA02
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09BB07
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09BB07
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09XA53
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C10BX09
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09XA54
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C07FB13
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DX03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09BX03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB04
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
NDF-RT N0000000069
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DX01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB07
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DX06
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC08GA02
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB07
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 12.3
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C10BX11
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DX03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB02
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB06
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
NDF-RT N0000007556
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09BB04
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB06
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C08CA01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC10BX03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09DB05
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09BX01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-VATC QC09BB03
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DX01
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
WHO-ATC C09DB02
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
Code System Code Type Description
CHEBI
2668
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
PUBCHEM
2162
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
CHEBI
2669
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
NCI_THESAURUS
C61635
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
RXCUI
17767
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY RxNorm
MERCK INDEX
m1757
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID7022596
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
DRUG BANK
DB00381
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
SMS_ID
100000085259
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
LACTMED
Amlodipine
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
FDA UNII
1J444QC288
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
IUPHAR
6981
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
DRUG CENTRAL
183
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
MESH
D017311
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
EVMPD
SUB05467MIG
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
CAS
88150-42-9
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
DAILYMED
1J444QC288
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
HSDB
7079
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
INN
5729
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
ChEMBL
CHEMBL1491
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
WIKIPEDIA
AMLODIPINE
Created by admin on Fri Dec 15 17:13:24 UTC 2023 , Edited by admin on Fri Dec 15 17:13:24 UTC 2023
PRIMARY
Related Record Type Details
VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1D
TARGET -> INHIBITOR
VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2
TARGET -> INHIBITOR
Structure of LEVAMLODIPINE
ENANTIOMER -> RACEMATE
Structure of AMLODIPINE
EXCRETED UNCHANGED->SUBSTANCE
AMOUNT EXCRETED
PLASMA; URINE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of AMLODIPINE MESYLATE MONOHYDRATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE BESYLATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE ADIPATE
SALT/SOLVATE -> PARENT
VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1
TARGET -> INHIBITOR
Structure of AMLODIPINE BESYLATE MONOHYDRATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE BENZOATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE OROTATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE MALEATE
SALT/SOLVATE -> PARENT
VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S
TARGET -> INHIBITOR
ALDEHYDE OXIDASE
METABOLIC ENZYME -> INHIBITOR
IC50
Structure of DEHYDROAMLODIPINE
DEGRADENT -> PARENT
VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C
TARGET -> INHIBITOR
Structure of Amlodipine nicotinate
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE BESYLATE DIHYDRATE
SALT/SOLVATE -> PARENT
Structure of AMLODIPINE, (R)-
ENANTIOMER -> RACEMATE
Structure of AMLODIPINE MESYLATE
SALT/SOLVATE -> PARENT
VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1I
TARGET -> INHIBITOR
Structure of AMLODIPINE CAMSYLATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of 2-((CARBOXYMETHOXY)METHYL)-4-(2-CHLOROPHENYL)-6-METHYL-3-PYRIDINECARBOXYLIC ACID, 3-ETHYL ESTER
METABOLITE INACTIVE -> PARENT
Structure of 2-((4-(2-CHLOROPHENYL)-3-ETHOXYCARBONYL-5-METHOXYCARBONYL-6-METHYL-2-PYRIDYL)METHOXY)ACETIC ACID
METABOLITE INACTIVE -> PARENT
Structure of 2,3,5-PYRIDINETRICARBOXYLIC ACID, 4-(2-CHLOROPHENYL)-6-METHYL-, 3-ETHYL 5-METHYL ESTER
METABOLITE INACTIVE -> PARENT
Structure of DEHYDROAMLODIPINE
METABOLITE INACTIVE -> PARENT
Structure of 2-((CARBOXYMETHOXY)METHYL)-4-(2-CHLOROPHENYL)-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID, 3-ETHYL ESTER
METABOLITE INACTIVE -> PARENT
Related Record Type Details
Structure of AMLODIPINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
ORAL BIOAVAILABILITY PHARMACOKINETIC
MAXIMUM TOLERATED DOSE PHARMACOKINETIC
Tmax PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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