U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C19H24N2O.ClH
Molecular Weight 332.868
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PALONOSETRON HYDROCHLORIDE

SMILES

Cl.[H][C@]12CCCC3=C1C(=CC=C3)C(=O)N(C2)[C@@H]4CN5CCC4CC5

InChI

InChIKey=OLDRWYVIKMSFFB-SSPJITILSA-N
InChI=1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1

HIDE SMILES / InChI
Molecular Formula C19H24N2O
Molecular Weight 296.4067
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:53:58 UTC 2023
Edited
by admin
on Fri Dec 15 15:53:58 UTC 2023
Record UNII
23310D4I19
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PALONOSETRON HYDROCHLORIDE
EMA EPAR   MART.   MI   ORANGE BOOK   USAN   USP-RS   WHO-DD  
USAN  
Official Name English
PALONOSETRON HYDROCHLORIDE [MI]
Common Name English
PALONOSETRON HCL
Common Name English
PALONOSETRON HYDROCHLORIDE [MART.]
Common Name English
PALONOSETRON HYDROCHLORIDE [USP-RS]
Common Name English
PALONOSETRON HYDROCHLORIDE [JAN]
Common Name English
PALONOSETRON HYDROCHLORIDE [ORANGE BOOK]
Common Name English
AKYNZEO COMPONENT PALONOSETRON HYDROCHLORIDE
Brand Name English
PALONOCETRON HYDROCHLORIDE
JAN  
Common Name English
PALONOSETRON (AS HYDROCHLORIDE)
Common Name English
PALONOSETRON HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
PALONOSETRON HYDROCHLORIDE [USAN]
Common Name English
PALONOSETRON HYDROCHLORIDE [EMA EPAR]
Common Name English
RS-25259-197
Code English
ALOXI
Brand Name English
Palonosetron hydrochloride [WHO-DD]
Common Name English
PALONOSETRON HYDROCHLORIDE COMPONENT OF AKYNZEO
Brand Name English
(3AS)-2,3,3A,4,5,6-HEXAHYDRO-2-((3S)-3-QUINUCLIDINYL)-1H-BENZ(DE)ISOQUINOLIN-1-ONE MONOHYDROCHLORIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C94726
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
EMA ASSESSMENT REPORTS PALONOSETRON HOSPERIA (AUTHORIZED: CANCER, NAUSEA, VOMITING)
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
EMA ASSESSMENT REPORTS AKYNZEO (AUTHORIZED: NAUSEA)
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
EMA ASSESSMENT REPORTS ALOXI (AUTHORIZED: VOMITTING)
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
NCI_THESAURUS C267
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
EMA ASSESSMENT REPORTS AKYNZEO (AUTHORIZED: VOMITTING)
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
Code System Code Type Description
CHEBI
85157
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
CAS
135729-62-3
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
MERCK INDEX
m8368
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY Merck Index
FDA UNII
23310D4I19
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
NCI_THESAURUS
C47650
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
USAN
GG-58
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
PUBCHEM
6918303
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
EVMPD
SUB20365
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
ChEMBL
CHEMBL1189679
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
SMS_ID
100000089547
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
RXCUI
397405
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID8046610
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
DRUG BANK
DBSALT001057
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
DAILYMED
23310D4I19
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
RS_ITEM_NUM
1492200
Created by admin on Fri Dec 15 15:53:58 UTC 2023 , Edited by admin on Fri Dec 15 15:53:58 UTC 2023
PRIMARY
Related Record Type Details
Structure of PALONOSETRON
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of PALONOSETRON N-OXIDE
IMPURITY -> PARENT
Structure of DEHYDRO PALONOSETRON HYDROCHLORIDE
IMPURITY -> PARENT
Structure of PALONOSETRON HYDROCHLORIDE, (3R)-
IMPURITY -> PARENT
Structure of PALONOSETRON HYDROCHLORIDE, (3AR)-
IMPURITY -> PARENT
Structure of DEHYDRO PALONOSETRON N-OXIDE
IMPURITY -> PARENT
Related Record Type Details
Structure of PALONOSETRON
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966