TOZASERTIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H28N8OS
Molecular Weight	464.586
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TOZASERTIB

Structure Search

SMILES

CN1CCN(CC1)C2=NC(SC3=CC=C(NC(=O)C4CC4)C=C3)=NC(NC5=NNC(C)=C5)=C2

InChI

InChIKey=GCIKSSRWRFVXBI-UHFFFAOYSA-N

InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)

HIDE SMILES / InChI

Molecular Formula	C23H28N8OS
Molecular Weight	464.586
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:31:45 UTC 2023` Edited by `admin` on `Sat Dec 16 17:31:45 UTC 2023`
Record UNII	234335M86K
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TOZASERTIB

Official Name

English

VX-680

Code

English

tozasertib [INN]

Common Name

English

TOZASERTIB [USAN]

Common Name

English

Tozasertib [WHO-DD]

Common Name

English

N-[4-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}sulfanyl)phenyl]cyclopropanecarboxamide

Systematic Name

English

CYCLOPROPANECARBOXAMIDE, N-(4-((4-(4-METHYL-1-PIPERAZINYL)-6-((5-METHYL-1H-PYRAZOL-3-YL)AMINO)-2-PYRIMIDINYL)THIO)PHENYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C62556

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

Code System Code Type Description

FDA UNII

234335M86K

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

EVMPD

SUB130344

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

USAN

UU-16

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

ChEMBL

CHEMBL572878

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

PUBCHEM

5494449

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

INN

9007

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

WIKIPEDIA

Tozasertib

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

SMS_ID

100000156438

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

EPA CompTox

DTXSID10213609

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

CAS

639089-54-6

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

NCI_THESAURUS

C98053

Created by admin on Sat Dec 16 17:31:46 UTC 2023 , Edited by admin on Sat Dec 16 17:31:46 UTC 2023

PRIMARY

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