VISMODEGIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H14Cl2N2O3S
Molecular Weight	421.297
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VISMODEGIB

Structure Search

SMILES

CS(=O)(=O)C1=CC(Cl)=C(C=C1)C(=O)NC2=CC=C(Cl)C(=C2)C3=CC=CC=N3

InChI

InChIKey=BPQMGSKTAYIVFO-UHFFFAOYSA-N

InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)

HIDE SMILES / InChI

Molecular Formula	C19H14Cl2N2O3S
Molecular Weight	421.297
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:57:58 UTC 2023` Edited by `admin` on `Sat Dec 16 16:57:58 UTC 2023`
Record UNII	25X868M3DS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VISMODEGIB

Official Name

English

GDC-0449

Code

English

ERIVEDGE

Brand Name

English

vismodegib [INN]

Common Name

English

VISMODEGIB [VANDF]

Common Name

English

Vismodegib [WHO-DD]

Common Name

English

2-CHLORO-N-(4-CHLORO-3-PYRIDIN-2-YL)PHENYL)-4-(METHYLSULFONYL)BENZAMIDE

Common Name

English

BENZAMIDE, 2-CHLORO-N-(4-CHLORO-3-(2-PYRIDINYL)PHENYL)-4-(METHYLSULFONYL)-

Systematic Name

English

NSC-755986

Code

English

VISMODEGIB [USAN]

Common Name

English

NSC-747691

Code

English

VISMODEGIB [MI]

Common Name

English

VISMODEGIB [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2189

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

LIVERTOX

NBK548629

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

EMA ASSESSMENT REPORTS

ERIVEDGE (AUTHORIZED: CARCINOMA, BASAL CELL)

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

NDF-RT

N0000184149

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

WHO-ATC

L01XX43

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

WHO-VATC

QL01XX43

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

Code System Code Type Description

CAS

879085-55-9

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

DRUG BANK

DB08828

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

DRUG CENTRAL

4227

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

HSDB

8130

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

DAILYMED

25X868M3DS

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

EVMPD

SUB32354

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

INN

9311

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

USAN

WW-37

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

MERCK INDEX

m11477

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

Merck Index

NDF-RT

N0000184148

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

Smoothened Receptor Antagonists [MoA]

PUBCHEM

24776445

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID40236689

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

CHEBI

66903

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

SMS_ID

100000124371

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

WIKIPEDIA

Vismodegib

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

NSC

755986

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

NSC

747691

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL473417

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

RXCUI

1242987

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

RxNorm

IUPHAR

6975

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

LACTMED

Vismodegib

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

FDA UNII

25X868M3DS

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

NCI_THESAURUS

C74038

Created by admin on Sat Dec 16 16:57:59 UTC 2023 , Edited by admin on Sat Dec 16 16:57:59 UTC 2023

PRIMARY

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ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				SINGLE DOSE

Volume of Distribution	PHARMACOKINETIC