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Details

Stereochemistry RACEMIC
Molecular Formula C24H28F3N3O3
Molecular Weight 463.4926
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TAFENOQUINE

SMILES

COC1=NC2=C(C(C)=C1)C(OC3=CC=CC(=C3)C(F)(F)F)=C(OC)C=C2NC(C)CCCN

InChI

InChIKey=LBHLFPGPEGDCJG-UHFFFAOYSA-N
InChI=1S/C24H28F3N3O3/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3

HIDE SMILES / InChI
Molecular Formula C24H28F3N3O3
Molecular Weight 463.4926
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:19:57 UTC 2023
Edited
by admin
on Sat Dec 16 17:19:57 UTC 2023
Record UNII
262P8GS9L9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TAFENOQUINE
INN   MART.   MI   USAN   WHO-DD  
INN   USAN  
Official Name English
TAFENOQUINE [MI]
Common Name English
SB-252263-AAB
Code English
tafenoquine [INN]
Common Name English
TAFENOQUINE [MART.]
Common Name English
TAFENOQUINE [USAN]
Common Name English
Tafenoquine [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 385812
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
NCI_THESAURUS C271
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
Code System Code Type Description
MERCK INDEX
m10429
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY Merck Index
CAS
106635-80-7
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
WIKIPEDIA
Tafenoquine
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
EVMPD
SUB04666MIG
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
NCI_THESAURUS
C73006
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
PUBCHEM
115358
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
CHEBI
135752
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
MESH
C055852
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
FDA UNII
262P8GS9L9
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
DRUG BANK
DB06608
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
EPA CompTox
DTXSID90869466
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
RXCUI
2054023
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
LACTMED
Tafenoquine
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
DRUG CENTRAL
3578
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
USAN
AB-17
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
ChEMBL
CHEMBL298470
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
SMS_ID
100000092719
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
DAILYMED
262P8GS9L9
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
INN
7835
Created by admin on Sat Dec 16 17:20:00 UTC 2023 , Edited by admin on Sat Dec 16 17:20:00 UTC 2023
PRIMARY
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corrected for non-specific binding
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POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2
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BINDER->LIGAND
BINDING
OCT-2
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corrected for non-specific binding
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TARGET ORGANISM->INHIBITOR
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METABOLITE INACTIVE -> PARENT
Related Record Type Details
Structure of TAFENOQUINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Tmax PHARMACOKINETIC POST-DOSE

Biological Half-life PHARMACOKINETIC
NIH
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