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Details

Stereochemistry ACHIRAL
Molecular Formula C8H8N4
Molecular Weight 160.1759
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDRALAZINE

SMILES

NNC1=NN=CC2=C1C=CC=C2

InChI

InChIKey=RPTUSVTUFVMDQK-UHFFFAOYSA-N
InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)

HIDE SMILES / InChI
Molecular Formula C8H8N4
Molecular Weight 160.1759
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:03:49 UTC 2023
Edited
by admin
on Fri Dec 15 15:03:49 UTC 2023
Record UNII
26NAK24LS8
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
HYDRALAZINE
INN   MI   VANDF   WHO-DD  
INN  
Official Name English
1-HYDRAZINOPHTHALAZINE
Systematic Name English
HYDRALAZINE [MI]
Common Name English
hydralazine [INN]
Common Name English
DIHYDRALAZINE SULFATE, HYDRATED IMPURITY B [EP IMPURITY]
Common Name English
Hydralazine [WHO-DD]
Common Name English
NSC-126699
Code English
HYDRALAZINE [IARC]
Common Name English
HYDRALAZINE [VANDF]
Common Name English
PHTHALAZINE, 1-HYDRAZINO-
Systematic Name English
HIDRAL
Brand Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 334611
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
WHO-ATC C02DB02
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 12.3
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
FDA ORPHAN DRUG 166703
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
NDF-RT N0000175379
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
WHO-VATC QC02LG02
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
WHO-VATC QC02DB02
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
LIVERTOX NBK548580
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
NCI_THESAURUS C270
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
NDF-RT N0000175564
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
WHO-ATC C02LG02
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
Code System Code Type Description
CAS
86-54-4
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
CHEBI
5775
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
FDA UNII
26NAK24LS8
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
RXCUI
5470
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY RxNorm
DAILYMED
26NAK24LS8
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
IUPHAR
7326
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
NSC
126699
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
LACTMED
Hydralazine
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
PUBCHEM
3637
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
DRUG BANK
DB01275
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
EVMPD
SUB08059MIG
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
EPA CompTox
DTXSID4023129
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
ChEMBL
CHEMBL276832
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
WIKIPEDIA
HYDRALAZINE
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
SMS_ID
100000084193
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
INN
1
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
ECHA (EC/EINECS)
201-680-3
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
MERCK INDEX
m6072
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C62032
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
MESH
D006830
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
DRUG CENTRAL
1384
Created by admin on Fri Dec 15 15:03:50 UTC 2023 , Edited by admin on Fri Dec 15 15:03:50 UTC 2023
PRIMARY
Related Record Type Details
Structure of HYDRALAZINE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Structure of PURINE
INNOVATOR->PARENT
HYDRALAZINE POLISTIREX
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
Structure of N-ACETYLHYDRALAZINE
METABOLITE INACTIVE -> PARENT
Spontaneously cyclizes to the stable product 3-methyl-s-triazolo-[3,4-a]phthalazine (MTP).
Structure of HYDRALAZINE PYRUVIC ACID HYDRAZONE
METABOLITE INACTIVE -> PARENT
Structure of 3-HYDROXYMETHYL-S-TRIAZOLO(3,4-A)PHTHALAZINE
METABOLITE INACTIVE -> PARENT
Acetylation was proposed as the major pathway for hydralazine clearance, where the acetylated drug, 3-methyl-s-triazolo[3,4-a )phthalazine (ITI), may be further metabolized to 3-hydroxymethyl-s -triazolo(3,4-a)phthalazine
Structure of 4-(2-ACETYLHYDRAZINO)-PHTHALAZINONE
METABOLITE INACTIVE -> PARENT
Structure of 3-METHYLTRIAZOLO(3,4-A)PHTHALAZINE
METABOLITE INACTIVE -> PARENT
Related Record Type Details
Structure of DIHYDRALAZINE SULFATE, HYDRATED
PARENT -> IMPURITY
Related Record Type Details
Structure of HYDRALAZINE
ACTIVE MOIETY
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