DEFERIPRONE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9NO2
Molecular Weight	139.1519
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DEFERIPRONE

Structure Search

SMILES

CN1C=CC(=O)C(O)=C1C

InChI

InChIKey=TZXKOCQBRNJULO-UHFFFAOYSA-N

InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3

HIDE SMILES / InChI

Molecular Formula	C7H9NO2
Molecular Weight	139.1519
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:47:54 UTC 2023` Edited by `admin` on `Fri Dec 15 15:47:54 UTC 2023`
Record UNII	2BTY8KH53L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DEFERIPRONE

Official Name

English

4(1H)-PYRIDINONE, 3-HYDROXY-1,2-DIMETHYL-

Systematic Name

English

DEFERIPRONE [EP MONOGRAPH]

Common Name

English

NSC-758880

Code

English

L-1

Code

English

3-Hydroxy-1,2-dimethylpyridin-4(1H)-one

Systematic Name

English

APO-66

Code

English

DEFERIPRONE [MART.]

Common Name

English

Deferiprone [WHO-DD]

Common Name

English

L1

Code

English

DEFERIPRONE [ORANGE BOOK]

Common Name

English

3-HYDROXY-1,2-DIMETHYL-4(1H)-PYRIDONE

Systematic Name

English

deferiprone [INN]

Common Name

English

DEFERIPRONE [EMA EPAR]

Common Name

English

CP-20

Code

English

DN-180-01-AF

Code

English

DEFERIPRONE [VANDF]

Common Name

English

DN-18001AF

Code

English

CP20

Code

English

DEFERIPRONE [USAN]

Common Name

English

APO-066

Code

English

DEFERIPRONE [MI]

Common Name

English

DEFERIPRON

Common Name

English

PL1

Code

English

PL-1

Code

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/10/832

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

NCI_THESAURUS

C62357

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

FDA ORPHAN DRUG

340011

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

FDA ORPHAN DRUG

581217

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

FDA ORPHAN DRUG

264308

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

EMA ASSESSMENT REPORTS

FERRIPOX (AUTHORIZED: BETA-THALASSEMIA)

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

LIVERTOX

NBK548086

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

FDA ORPHAN DRUG

150701

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

NDF-RT

N0000175522

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

WHO-ATC

V03AC02

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

WHO-VATC

QV03AC02

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

Code System Code Type Description

WIKIPEDIA

DEFERIPRONE

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

CAS

30652-11-0

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

ChEMBL

CHEMBL70927

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

CHEBI

68554

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

SMS_ID

100000085431

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

INN

6958

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

MESH

C044919

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

DRUG BANK

DB08826

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

RXCUI

11645

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m4132

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

Merck Index

IUPHAR

7456

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

DAILYMED

2BTY8KH53L

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

DRUG CENTRAL

4188

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

USAN

WW-29

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

EPA CompTox

DTXSID6040666

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

EVMPD

SUB06941MIG

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

FDA UNII

2BTY8KH53L

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

NSC

758880

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

LACTMED

Deferiprone

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

NCI_THESAURUS

C73030

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

HSDB

8335

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

PUBCHEM

2972

Created by admin on Fri Dec 15 15:47:54 UTC 2023 , Edited by admin on Fri Dec 15 15:47:54 UTC 2023

PRIMARY

Related Record Type Details


					3318TFY23Q

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					S0025AG5ZT

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A10

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					91O4LML611

TARGET->LIGAND


					S5EY2C8G0B

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A8

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					2BTY8KH53L

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					2BTY8KH53L

EXCRETED UNCHANGED

Qualification:

URINE

Amount:

Related Record Type Details


					2FF8DPG57Y

3-HYDROXY-2-(HYDROXYMETHYL)-1-METHYL-4(1H)-PYRIDINONE

METABOLITE -> PARENT


					47N4BZV3Z9

(2S,3S,4S,5R,6S)-3,4,5-TRIHYDROXY-6-((2-(HYDROXYMETHYL)-1-METHYL-4-OXO-3-PYRIDYL)OXY)TETRAHYDROPYRAN-2-CARBOXYLIC ACID

METABOLITE -> PARENT


					BV1G5BFA7Z

3-METHOXY-1,2-DIMETHYL-PYRIDIN-4-ONE

METABOLITE -> PARENT


					1QOS5ADQ2R

DEFERIPRONE 3-O-.BETA.-D-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Related Record Type Details


					W0JGJ7373Y

1-METHYL-3-(METHYLAMINO)-1,5-DIHYDRO-2H-PYRROL-2-ONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					3A9RD92BS4

MALTOL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					2BTY8KH53L

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				SINGLE DOSE IN THE FED STATE

Tmax	PHARMACOKINETIC				SINGLE DOSE IN FASTED HEALTHY SUBJECTS

Biological Half-life	PHARMACOKINETIC