ISTRADEFYLLINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H24N4O4
Molecular Weight	384.429
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of ISTRADEFYLLINE

Structure Search

SMILES

CCN1C2=C(N(C)C(\C=C\C3=CC(OC)=C(OC)C=C3)=N2)C(=O)N(CC)C1=O

InChI

InChIKey=IQVRBWUUXZMOPW-PKNBQFBNSA-N

InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+

HIDE SMILES / InChI

Molecular Formula	C20H24N4O4
Molecular Weight	384.429
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:52:37 UTC 2023` Edited by `admin` on `Sat Dec 16 17:52:37 UTC 2023`
Record UNII	2GZ0LIK7T4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ISTRADEFYLLINE

Official Name

English

KW-6002

Code

English

(E)-8-(3,4-DIMETHOXYSTYRYL)-1,3-DIETHYL-7-METHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE

Systematic Name

English

Istradefylline [WHO-DD]

Common Name

English

8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione

Systematic Name

English

1H-PURINE-2,6-DIONE, 8-((1E)-2-(3,4-DIMETHOXYPHENYL)ETHENYL)-1,3-DIETHYL-3,7-DIHYDRO-7-METHYL-

Systematic Name

English

ISTRADEFYLLINE [USAN]

Common Name

English

ISTRADEFYLLINE [MI]

Common Name

English

ISTRADEFYLLINE [JAN]

Common Name

English

istradefylline [INN]

Common Name

English

NOURIANZ

Brand Name

English

ISTRADEFYLLINE [ORANGE BOOK]

Common Name

English

NOURIAST

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C38149

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

Code System Code Type Description

MERCK INDEX

m6559

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

Merck Index

JAPANESE REVIEW

NOURIAST

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

APPROVED MARCH 2013

PUBCHEM

5311037

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

RXCUI

2199015

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

INN

8387

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

DRUG BANK

DB11757

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

ChEMBL

CHEMBL431770

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

CAS

155270-99-8

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

DAILYMED

2GZ0LIK7T4

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

EPA CompTox

DTXSID7057652

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

WIKIPEDIA

ISTRADEFYLLINE

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

FDA UNII

2GZ0LIK7T4

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

MESH

C111599

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

NCI_THESAURUS

C73268

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

SMS_ID

100000152133

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

EVMPD

SUB126676

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

DRUG CENTRAL

4882

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

USAN

OO-61

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

IUPHAR

5608

Created by admin on Sat Dec 16 17:52:40 UTC 2023 , Edited by admin on Sat Dec 16 17:52:40 UTC 2023

PRIMARY

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					5EM6OCN637

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					G2E7E4E4HK

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					I2P9NA76OG

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					2GZ0LIK7T4

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC