VARESPLADIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H20N2O5
Molecular Weight	380.3939
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VARESPLADIB

Structure Search

SMILES

CCC1=C(C(=O)C(N)=O)C2=C(OCC(O)=O)C=CC=C2N1CC3=CC=CC=C3

InChI

InChIKey=BHLXTPHDSZUFHR-UHFFFAOYSA-N

InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)

HIDE SMILES / InChI

Molecular Formula	C21H20N2O5
Molecular Weight	380.3939
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:26:33 UTC 2023` Edited by `admin` on `Fri Dec 15 16:26:33 UTC 2023`
Record UNII	2Q3P98DATH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VARESPLADIB

Official Name

English

VARESPLADIB [USAN]

Common Name

English

ACETIC ACID, ((3-(AMINOOXOACETYL)-2-ETHYL-1-(PHENYLMETHYL)-1H-INDOL-4-YL)OXY)-

Common Name

English

LY-315920

Code

English

((3-(AMINO(OXO)ACETYL)-1-BENZYL-2-ETHYL-1H-INDOL-4-YL)OXY)ACETIC ACID

Systematic Name

English

Varespladib [WHO-DD]

Common Name

English

varespladib [INN]

Common Name

English

VARESPLADIB [MI]

Common Name

English

LY315920

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

FDA ORPHAN DRUG

677919

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID50169378

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

ChEMBL

CHEMBL148674

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

DRUG BANK

DB11909

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

MERCK INDEX

m11396

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

Merck Index

FDA UNII

2Q3P98DATH

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

PUBCHEM

155815

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

NCI_THESAURUS

C152832

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

WIKIPEDIA

VARESPLADIB

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

INN

8243

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

USAN

UU-55

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

CAS

172732-68-2

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

EVMPD

SUB25685

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

SMS_ID

100000091706

Created by admin on Fri Dec 15 16:26:33 UTC 2023 , Edited by admin on Fri Dec 15 16:26:33 UTC 2023

PRIMARY

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VARESPLADIB SODIUM

SALT/SOLVATE -> PARENT


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PHOSPHOLIPASE A2, MEMBRANE ASSOCIATED

TARGET -> INHIBITOR

Qualification:

IC50

Amount:


					NN8F8MP75S

CALCIUM-DEPENDENT PHOSPHOLIPASE A2

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					L2081J5KJN

GROUP 10 SECRETORY PHOSPHOLIPASE A2

TARGET -> INHIBITOR

Qualification:

IC50

Amount:

Related Record Type Details


					0NB98NBX3D

VARESPLADIB METHYL

PRODRUG -> METABOLITE ACTIVE

Related Record Type Details


					2Q3P98DATH

ACTIVE MOIETY