MAPROTILINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H23N
Molecular Weight	277.4033
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MAPROTILINE

Structure Search

SMILES

CNCCCC12CCC(C3=CC=CC=C13)C4=CC=CC=C24

InChI

InChIKey=QSLMDECMDJKHMQ-UHFFFAOYSA-N

InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3

HIDE SMILES / InChI

Molecular Formula	C20H23N
Molecular Weight	277.4033
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:06:48 UTC 2023` Edited by `admin` on `Fri Dec 15 15:06:48 UTC 2023`
Record UNII	2U1W68TROF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MAPROTILINE

Official Name

English

N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine

Systematic Name

English

BA-34,276 FREE BASE

Code

English

MAPROTILINE [MART.]

Common Name

English

maprotiline [INN]

Common Name

English

MAPROTILINE [MI]

Common Name

English

Maprotiline [WHO-DD]

Common Name

English

MAPROTILINE [USAN]

Common Name

English

BA-34276 FREE BASE

Code

English

9,10-ETHANOANTHRACENE-9(10H)-PROPANAMINE, N-METHYL-

Systematic Name

English

MAPROTILINE [VANDF]

Common Name

English

Classification Tree Code System Code

LIVERTOX

581

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

WHO-ATC

N06AA21

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

WHO-VATC

QN06AA21

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

NCI_THESAURUS

C265

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID7045029

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

NCI_THESAURUS

C61824

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

DRUG CENTRAL

1634

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

ECHA (EC/EINECS)

233-599-4

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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DRUG BANK

DB00934

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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LACTMED

Maprotiline

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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MERCK INDEX

m7083

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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Merck Index

CAS

10262-69-8

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

ChEMBL

CHEMBL21731

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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INN

2763

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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SMS_ID

100000091525

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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EVMPD

SUB08647MIG

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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FDA UNII

2U1W68TROF

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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WIKIPEDIA

MAPROTILINE

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

PUBCHEM

4011

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

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RXCUI

6646

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

RxNorm

IUPHAR

2402

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

MESH

D008376

Created by admin on Fri Dec 15 15:06:48 UTC 2023 , Edited by admin on Fri Dec 15 15:06:48 UTC 2023

PRIMARY

Related Record Type Details


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					7C8J54PVFI

MAPROTILINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					22P65W41V0

MAPROTILINE MESYLATE

SALT/SOLVATE -> PARENT


					LR0F81F33L

ALDEHYDE OXIDASE

METABOLIC ENZYME -> INHIBITOR

Qualification:

IC50

Amount:

Related Record Type Details


					G1GL9J364N

DESMETHYLMAPROTILINE

METABOLITE -> PARENT

Amount:

Related Record Type Details


					2U1W68TROF

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC