ESTAZOLAM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H11ClN4
Molecular Weight	294.738
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ESTAZOLAM

Structure Search

SMILES

ClC1=CC2=C(C=C1)N3C=NN=C3CN=C2C4=CC=CC=C4

InChI

InChIKey=CDCHDCWJMGXXRH-UHFFFAOYSA-N

InChI=1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2

HIDE SMILES / InChI

Molecular Formula	C16H11ClN4
Molecular Weight	294.738
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:23:27 UTC 2023` Edited by `admin` on `Fri Dec 15 15:23:27 UTC 2023`
Record UNII	36S3EQV54C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ESTAZOLAM

Official Name

English

NSC-290818

Code

English

ESTAZOLAM [USAN]

Common Name

English

ABBOTT-47631

Code

English

ESTAZOLAM [VANDF]

Common Name

English

ESTAZOLAM [IARC]

Common Name

English

ESTAZOLAM [USP MONOGRAPH]

Common Name

English

ESTAZOLAM [MI]

Common Name

English

Estazolam [WHO-DD]

Common Name

English

ESTAZOLAM CIV [USP-RS]

Common Name

English

ESTAZOLAM [JAN]

Common Name

English

ESTAZOLAM CIV

Common Name

English

8-Chloro-6-phenyl-4H-S-triazolo[4,3-a][1,4]benzodiazepine

Systematic Name

English

4H-(1,2,4)TRIAZOLO(4,3-A)(1,4)BENZODIAZEPINE, 8-CHLORO-6-PHENYL-

Systematic Name

English

ESTAZOLAM [MART.]

Common Name

English

estazolam [INN]

Common Name

English

PROSOM

Brand Name

English

ESTAZOLAM [ORANGE BOOK]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1012

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

WHO-ATC

N05CD04

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

NDF-RT

N0000007542

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

LIVERTOX

NBK548660

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

WHO-VATC

QN05CD04

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

NDF-RT

N0000175694

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

DEA NO.

2756

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C47520

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

MESH

D004949

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

USAN

CC-24

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

PUBCHEM

3261

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

DAILYMED

36S3EQV54C

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

EVMPD

SUB07241MIG

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

DRUG CENTRAL

1056

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

RS_ITEM_NUM

1249905

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

IUPHAR

7550

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

RXCUI

4077

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

RxNorm

LACTMED

Estazolam

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

DRUG BANK

DB01215

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

SMS_ID

100000082361

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

WIKIPEDIA

ESTAZOLAM

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

ChEMBL

CHEMBL285674

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

FDA UNII

36S3EQV54C

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

INN

3611

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

ECHA (EC/EINECS)

249-982-4

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

MERCK INDEX

m5027

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

Merck Index

EPA CompTox

DTXSID5020572

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

NSC

290818

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

CHEBI

4858

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

CAS

29975-16-4

Created by admin on Fri Dec 15 15:23:28 UTC 2023 , Edited by admin on Fri Dec 15 15:23:28 UTC 2023

PRIMARY

Related Record Type Details


					36S3EQV54C

ESTAZOLAM

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:

Related Record Type Details


					G4JQ545FZL

METABOLITE LESS ACTIVE -> PARENT

Comments:

m. 1-0x0-estazolam was about five times less effective than the parent drug in terms of brain concn. necessary to disrupt rota-rod performance but only twice in respect to the anticonvulsant activity.


					5EMY6HB5FL

4-HYDROXYESTAZOLAM

METABOLITE -> PARENT


					BZC06G3KPK

4'-HYDROXYESTAZOLAM

METABOLITE -> PARENT


					MKU3PJF3WP

4-HYDROXYESTAZOLAM GLUCURONIDE

METABOLITE -> PARENT


					CKE2KB8QZ4

4-HYDROXYL-1-OXOESTAZOLAM

METABOLITE -> PARENT


					HA7GSQ3MM7

CONJUGATED 4'-HYDROXYESTAZOLAM

METABOLITE -> PARENT

Related Record Type Details


					8D2N5WQ113

2-(N-CHLOROACETYL-N-CHLOROACETYLHYDRAZONOMETHYL)AMINO-5-CHLOROBENZOPHENONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					X9BHM4Q3UB

(5-CHLORO-2-(3-ETHYL-4H-1,2,4-TRIAZOL-4-YL)PHENYL)PHENYLMETHANONE

IMPURITY -> PARENT


					PN6505V1YM

5-CHLORO-2-(CHLOROACETAMIDO)BENZOPHENONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					FR80014ZBT

OXAZEPAM BENZOPHENONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					4T5QEZ5XFM

(5-CHLORO-2-(3-(CHLOROMETHYL)-4H-1,2,4-TRIAZOL-4-YL)PHENYL) PHENYL KETONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					67220MCM01

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					T620ANU9VW

5-CHLORO-2-FORMAMIDOBENZOPHENONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					36S3EQV54C

ESTAZOLAM

ACTIVE MOIETY