CEFTOLOZANE

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C23H30N12O8S2
Molecular Weight	666.69
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CEFTOLOZANE

Structure Search

SMILES

[H][C@]12SCC(C[N+]3=CC(NC(=O)NCCN)=C(N)N3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C(O)=O)\C4=NSC(N)=N4)C([O-])=O

InChI

InChIKey=JHFNIHVVXRKLEF-DCZLAGFPSA-N

InChI=1S/C23H30N12O8S2/c1-23(2,20(40)41)43-31-11(15-30-21(26)45-32-15)16(36)29-12-17(37)35-13(19(38)39)9(8-44-18(12)35)6-34-7-10(14(25)33(34)3)28-22(42)27-5-4-24/h7,12,18,25H,4-6,8,24H2,1-3H3,(H7,26,27,28,29,30,32,36,38,39,40,41,42)/b31-11-/t12-,18-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C23H30N12O8S2
Molecular Weight	666.69
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 20:39:38 UTC 2023` Edited by `admin` on `Fri Dec 15 20:39:38 UTC 2023`
Record UNII	37A4IES95Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEFTOLOZANE

Official Name

English

CXA-101 FREE BASE

Code

English

CEFTOLOZANE [MI]

Common Name

English

Ceftolozane [WHO-DD]

Common Name

English

(6R,7R)-3-((5-AMINO-4-(((2-AMINOETHYL)CARBAMOYL)AMINO)-1-METHYL-1H-PYRAZOL-2-IUM-2-YL)METHYL)-7-((2Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-(((2-CARBOXYPROPAN-2-YL)OXY)IMINO)ACETAMIDO)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLATE

Common Name

English

CEFTOLOZANE [USAN]

Common Name

English

ceftolozane [INN]

Common Name

English

CEFTOLOZANE [VANDF]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175488

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

LIVERTOX

NBK547862

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

LIVERTOX

NBK548666

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

WHO-ATC

J01DI54

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

NCI_THESAURUS

C357

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

Code System Code Type Description

CAS

689293-68-3

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

ChEMBL

CHEMBL2103872

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

WIKIPEDIA

Ceftolozane

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

EVMPD

SUB167762

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

RXCUI

1597609

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

RxNorm

PUBCHEM

53234134

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

INN

9426

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

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EPA CompTox

DTXSID901031217

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

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MERCK INDEX

m3224

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

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Merck Index

NCI_THESAURUS

C150024

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

SMS_ID

100000158130

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

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DAILYMED

37A4IES95Q

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

LACTMED

Ceftolozane and Tazobactam

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

CHEBI

134719

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

DRUG CENTRAL

4922

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

FDA UNII

37A4IES95Q

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

DRUG BANK

DB09050

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

USAN

WW-81

Created by admin on Fri Dec 15 20:39:38 UTC 2023 , Edited by admin on Fri Dec 15 20:39:38 UTC 2023

PRIMARY

Related Record Type Details


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					37A4IES95Q

EXCRETED UNCHANGED

Amount:


					Y793W5V55N

PSEUDOMONAS AERUGINOSA

TARGET ORGANISM->INHIBITOR

Amount:


					37A4IES95Q

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					7R247U84HY

CEFTOLOZANE SULFATE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					37A4IES95Q

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC