MECLIZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C25H27ClN2
Molecular Weight	390.948
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MECLIZINE

Structure Search

SMILES

CC1=CC=CC(CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4)=C1

InChI

InChIKey=OCJYIGYOJCODJL-UHFFFAOYSA-N

InChI=1S/C25H27ClN2/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23/h2-13,18,25H,14-17,19H2,1H3

HIDE SMILES / InChI

Molecular Formula	C25H27ClN2
Molecular Weight	390.948
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:17:01 UTC 2023` Edited by `admin` on `Fri Dec 15 17:17:01 UTC 2023`
Record UNII	3L5TQ84570
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MECLIZINE

Common Name

English

meclozine [INN]

Common Name

English

1-(P-CHLORO-.ALPHA.-PHENYLBENZYL)-4-(M-METHYLBENZYL)PIPERAZINE

Common Name

English

MECLIZINE [MI]

Common Name

English

NSC-169189

Code

English

MECLIZINE [VANDF]

Common Name

English

Meclozine [WHO-DD]

Common Name

English

MECLOZINE

Official Name

English

MECLIZINE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

WHO-ATC

R06AE05

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

WHO-ATC

R06AE55

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

WHO-VATC

QR06AE55

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

LIVERTOX

NBK547895

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

WHO-VATC

QR06AE05

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

NDF-RT

N0000178372

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

NCI_THESAURUS

C267

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

NDF-RT

N0000009034

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

NDF-RT

N0000009034

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

Code System Code Type Description

RXCUI

6676

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

RxNorm

DRUG BANK

DB00737

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

PUBCHEM

4034

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

WIKIPEDIA

MECLOZINE

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

ChEMBL

CHEMBL1623

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

EVMPD

SUB08685MIG

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

NCI_THESAURUS

C61610

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

LACTMED

Meclizine

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

FDA UNII

3L5TQ84570

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

DRUG CENTRAL

1649

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

NSC

169189

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

SMS_ID

100000081967

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

MERCK INDEX

m7118

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

Merck Index

IUPHAR

2757

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

ECHA (EC/EINECS)

209-323-3

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

DAILYMED

3L5TQ84570

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

MESH

D008468

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

HSDB

3113

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

INN

204

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

EPA CompTox

DTXSID0023242

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

CAS

569-65-3

Created by admin on Fri Dec 15 17:17:01 UTC 2023 , Edited by admin on Fri Dec 15 17:17:01 UTC 2023

PRIMARY

Related Record Type Details


					EY5P458MU3

MECLIZINE, (R)-

ENANTIOMER -> RACEMATE


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> NON-SUBSTRATE


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> NON-SUBSTRATE


					LV0F32NYUF

MECLIZINE, (S)-

ENANTIOMER -> RACEMATE


					28XBT591QG

HISTAMINE H1 RECEPTOR

TARGET -> INHIBITOR


					008PUV3986

MECLIZINE MONOHYDROCHLORIDE

SALT/SOLVATE -> PARENT


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Comments:

RECOMBINANT ENZYME

Interaction Type:

SUBSTRATE

Qualification:

Km

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

SUBSTRATE

Qualification:

Vmax

Amount:


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> NON-SUBSTRATE


					HDP7W44CIO

MECLIZINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					L997QXC9J1

MECLIZINE HYDROCHLORIDE ANHYDROUS

SALT/SOLVATE -> PARENT

Related Record Type Details


					UDU7KUV9VL

Meclizine N-oxide

METABOLITE -> PARENT

Amount:


					9MQ6K724K8

Meclizine N',N''-Dioxide

METABOLITE -> PARENT

Amount:

Related Record Type Details


					3L5TQ84570

MECLIZINE

ACTIVE MOIETY