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Details

Stereochemistry ACHIRAL
Molecular Formula C22H22ClN6O.K
Molecular Weight 461.001
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LOSARTAN POTASSIUM

SMILES

[K+].CCCCC1=NC(Cl)=C(CO)N1CC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=N[N-]4

InChI

InChIKey=OXCMYAYHXIHQOA-UHFFFAOYSA-N
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1

HIDE SMILES / InChI
Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C22H22ClN6O
Molecular Weight 421.903
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:43:46 UTC 2023
Edited
by admin
on Fri Dec 15 15:43:46 UTC 2023
Record UNII
3ST302B24A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LOSARTAN POTASSIUM
EP   HSDB   JAN   MART.   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN  
Official Name English
TANCIN
Common Name English
LOSARTAN POTASSIUM [EP MONOGRAPH]
Common Name English
LOSARTAN MONOPOTASSIUM SALT
MI  
Common Name English
LOSATA
Common Name English
LOSACAR
Common Name English
HYZAAR COMPONENT LOSARTAN POTASSIUM
Common Name English
LOSARTAN POTASSIUM [USP MONOGRAPH]
Common Name English
LOSARTAN POTASSIUM [VANDF]
Common Name English
COZAAR
Brand Name English
LOSARTAN POTASSIUM [JAN]
Common Name English
NU-LOTAN
Common Name English
DUP753
Code English
LOSARTAN POTASSIUM [USAN]
Common Name English
LOSARTAN POTASSIUM [ORANGE BOOK]
Common Name English
LOSARTAN POTASSIUM [HSDB]
Common Name English
LOSARTAN MONOPOTASSIUM SALT [MI]
Common Name English
LOSARTAN POTASSIUM [MART.]
Common Name English
MK0954
Code English
ARADOIS
Common Name English
L-158086
Code English
2-BUTYL-4-CHLORO-1-(P-(O-1H-TETRAZOL-5-YLPHENYL)BENZYL)IMIDAZOLE-5-METHANOL, MONOPOTASSIUM SALT
Common Name English
1H-IMIDAZOLE-5-METHANOL, 2-BUTYL-4-CHLORO-1-((2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-, MONOPOTASSIUM SALT
Common Name English
MK-0954
Code English
ZAART
Common Name English
LOSARTAN POTASSIUM [USP-RS]
Common Name English
DU PONT-753
Code English
E-3340
Code English
LOSARTAN POTASSIUM COMPONENT OF HYZAAR
Common Name English
Losartan potassium [WHO-DD]
Common Name English
DUP-753
Code English
PRESARTAN-50
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C66930
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
Code System Code Type Description
RS_ITEM_NUM
1370462
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
ChEMBL
CHEMBL191
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
PUBCHEM
11476710
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
EVMPD
SUB02974MIG
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
NCI_THESAURUS
C29165
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
CAS
124750-99-8
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
EPA CompTox
DTXSID3044209
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
DAILYMED
3ST302B24A
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
USAN
CC-73
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
RXCUI
203160
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY RxNorm
DRUG BANK
DBSALT000112
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
MERCK INDEX
m6911
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY Merck Index
FDA UNII
3ST302B24A
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
SMS_ID
100000091442
Created by admin on Fri Dec 15 15:43:46 UTC 2023 , Edited by admin on Fri Dec 15 15:43:46 UTC 2023
PRIMARY
Related Record Type Details
Structure of LOSARTAN
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of 2-BUTYL-5-CHLORO-1H-IMIDAZOLE-4-CARBALDEHYDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of N1-LOSARTANYL-LOSARTAN
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (2-BUTYL-5-CHLORO-1-((2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHYL)-1H-IMIDAZOL-4-YL)METHANOL
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of TRITYLLOSARTAN
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of TRIPHENYLCARBINOL
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of N2-LOSARTANYL-LOSARTAN
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-(4'-((2-BUTYL-4-CHLORO-5-(((1-METHYLETHYL)OXY)METHYL)-1H-IMIDAZOL-1-YL)METHYL)BIPHENYL-2-YL)-1H-TETRAZOLE
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (2'-(1H-TETRAZOL-5-YL)BIPHENYL-4-YL)METHANOL
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of LOSARTAN TRITYL ETHER
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of O-ACETYL LOSARTAN
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of N-NITROSO-N-METHYL-4-AMINOBUTYRIC ACID
IMPURITY GENOTOXIC->PARENT
Losartan potassium tablets made by Hetero Labs and distributed by Camber Pharmaceuticals contain the impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA), which is a known animal and potential human carcinogen.
Structure of LOSARTAN CARBOXALDEHYDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of L-158507
IMPURITY -> PARENT
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of LOSARTAN
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