FILGOTINIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23N5O3S
Molecular Weight	425.504
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FILGOTINIB

Structure Search

SMILES

O=C(NC1=NN2C(C=CC=C2C3=CC=C(CN4CCS(=O)(=O)CC4)C=C3)=N1)C5CC5

InChI

InChIKey=RIJLVEAXPNLDTC-UHFFFAOYSA-N

InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)

HIDE SMILES / InChI

Molecular Formula	C21H23N5O3S
Molecular Weight	425.504
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:52:56 UTC 2023` Edited by `admin` on `Sat Dec 16 04:52:56 UTC 2023`
Record UNII	3XVL385Q0M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FILGOTINIB

Official Name

English

GS-6034 FREE BASE

Code

English

CYCLOPROPANECARBOXAMIDE, N-(5-(4-((1,1-DIOXIDO-4-THIOMORPHOLINYL)METHYL)PHENYL)(1,2,4)TRIAZOLO(1,5-A)PYRIDIN-2-YL)-

Systematic Name

English

FILGOTINIB [USAN]

Common Name

English

Filgotinib [WHO-DD]

Common Name

English

filgotinib [INN]

Common Name

English

G-146034

Code

English

G146034

Code

English

N-(5-(4-((1,1-OXO-.LAMBDA.6-THIOMORPHOLIN-4-YL)METHYL)PHENYL((1,2,4)TRIAZOLO(1,5-A)PYRIDIN-2-YL)CYCLOPROPANECARBOXAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C155799

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

ChEMBL

CHEMBL3301607

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

FDA UNII

3XVL385Q0M

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

EVMPD

SUB182273

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

EPA CompTox

DTXSID80152935

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

PUBCHEM

49831257

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

WIKIPEDIA

Filgotinib

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

USAN

BC-110

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

CAS

1206161-97-8

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

SMS_ID

100000168720

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

INN

9720

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

DRUG BANK

DB14845

Created by admin on Sat Dec 16 04:52:57 UTC 2023 , Edited by admin on Sat Dec 16 04:52:57 UTC 2023

PRIMARY

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TYROSINE-PROTEIN KINASE JAK2

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FILGOTINIB HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


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FILGOTINIB MALEATE

SALT/SOLVATE -> PARENT

Amount:


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PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					08S4A2S6FT

TYROSINE-PROTEIN KINASE JAK1

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ACTIVE MOIETY

Amount: