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Details

Stereochemistry ACHIRAL
Molecular Formula C15H14FN3O3
Molecular Weight 303.2884
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUMAZENIL

SMILES

CCOC(=O)C1=C2CN(C)C(=O)C3=C(C=CC(F)=C3)N2C=N1

InChI

InChIKey=OFBIFZUFASYYRE-UHFFFAOYSA-N
InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C15H14FN3O3
Molecular Weight 303.2884
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:09:57 UTC 2023
Edited
by admin
on Fri Dec 15 15:09:57 UTC 2023
Record UNII
40P7XK9392
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUMAZENIL
EP   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
ANEXATE
Brand Name English
FLUMAZENIL [USAN]
Common Name English
RO-15-1788
Code English
FLUMAZENIL [MI]
Common Name English
FLUMAZEPIL
Common Name English
Flumazenil [WHO-DD]
Common Name English
MAZICON
Brand Name English
FLUMAZENIL [USP-RS]
Common Name English
FLUMAZENIL [VANDF]
Common Name English
Ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
Systematic Name English
RO-151788
Code English
FLUMAZENIL [MART.]
Common Name English
RO-151788000
Code English
NSC-759193
Code English
RO 15-1788/000
Code English
RO-1722
Code English
FLUMAZENIL [EP MONOGRAPH]
Common Name English
FLUMAZENIL [ORANGE BOOK]
Common Name English
LANEXAT
Brand Name English
FLUMAZENIL [USP MONOGRAPH]
Common Name English
ROMAZICON
Brand Name English
4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER
Common Name English
flumazenil [INN]
Common Name English
RO-15-1788/000
Code English
FLUMAZENIL [JAN]
Common Name English
RO-41-8157
Code English
Classification Tree Code System Code
WHO-ATC V03AB25
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
WHO-VATC QV03AB25
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
NCI_THESAURUS C1012
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
NDF-RT N0000175680
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
Code System Code Type Description
INN
5311
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
RXCUI
4457
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY RxNorm
EVMPD
SUB07693MIG
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
PUBCHEM
3373
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
MERCK INDEX
m5436
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY Merck Index
SMS_ID
100000080704
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
DAILYMED
40P7XK9392
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
NCI_THESAURUS
C47534
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
EPA CompTox
DTXSID2023064
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
IUPHAR
4192
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
RS_ITEM_NUM
1273808
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
DRUG CENTRAL
1195
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
WIKIPEDIA
FLUMAZENIL
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
MESH
D005442
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
ChEMBL
CHEMBL407
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
CAS
78755-81-4
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
USAN
W-44
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
DRUG BANK
DB01205
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
NSC
759193
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
CHEBI
5103
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
FDA UNII
40P7XK9392
Created by admin on Fri Dec 15 15:09:57 UTC 2023 , Edited by admin on Fri Dec 15 15:09:57 UTC 2023
PRIMARY
Related Record Type Details
GABAA RECEPTOR (RAT)
TARGET -> INHIBITOR
IC50
GABAA RECEPTOR
TARGET -> INHIBITOR
Has been used as an antidote in the treatment of benzodiazepine and Z-drug overdoses.[
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
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Structure of N-DESMETHYLFLUMAZENIL
METABOLITE -> PARENT
probably by cytochrome P450
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Structure of FLUMAZENIL DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of DIMETHYLFORMAMIDE DIETHYLACETAL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (TLC)
USP
Structure of DESFLUORO FLUMAZENIL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of DESFLUORO HYDROXYFLUMAZENIL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of FLUMAZENIL ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of CHLOROFLUMAZENIL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of FLUMAZENIL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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