NATEGLINIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H27NO3
Molecular Weight	317.4226
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NATEGLINIDE

Structure Search

SMILES

CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](CC2=CC=CC=C2)C(O)=O

InChI

InChIKey=OELFLUMRDSZNSF-BRWVUGGUSA-N

InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H27NO3
Molecular Weight	317.4226
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:16:10 UTC 2023` Edited by `admin` on `Fri Dec 15 16:16:10 UTC 2023`
Record UNII	41X3PWK4O2
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NATEGLINIDE

Official Name

English

NATEGLINIDE [EP MONOGRAPH]

Common Name

English

DJN 608

Code

English

NATEGLINIDE [VANDF]

Common Name

English

NATEGLINIDE [USAN]

Common Name

English

D-PHENYLALANINE, N-((TRANS-4-(1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-

Systematic Name

English

STARSIS

Brand Name

English

NATEGLINIDE [ORANGE BOOK]

Common Name

English

NATEGLINIDE [USP MONOGRAPH]

Common Name

English

SDZ-DJN-608

Code

English

NATEGLINIDE [USP-RS]

Common Name

English

SDZ DJN 608

Code

English

STARLIX

Brand Name

English

DJN-608

Code

English

NATEGLINIDE [MI]

Common Name

English

D-NATEGLINIDE

Common Name

English

NSC-758695

Code

English

NATEGLINIDE [MART.]

Common Name

English

AY-4166

Code

English

nateglinide [INN]

Common Name

English

NATEGLINIDE [EMA EPAR]

Common Name

English

Nateglinide [WHO-DD]

Common Name

English

SENAGLINIDE

Common Name

English

A-4166

Code

English

NATEGLINIDE [JAN]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175428

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

NCI_THESAURUS

C98079

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

NDF-RT

N0000175448

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

WHO-ATC

A10BX03

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

WHO-VATC

QA10BX03

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

LIVERTOX

NBK548227

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL783

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

CHEBI

31897

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

CAS

105816-04-4

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

IUPHAR

6833

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

DAILYMED

41X3PWK4O2

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

MESH

C060142

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

WIKIPEDIA

NATEGLINIDE

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

USAN

MM-15

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

RXCUI

274332

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

RxNorm

SMS_ID

100000091326

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

EVMPD

SUB09170MIG

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

FDA UNII

41X3PWK4O2

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

LACTMED

Nateglinide

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

INN

7594

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

NCI_THESAURUS

C61858

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

MERCK INDEX

m7780

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

Merck Index

NSC

758695

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

RS_ITEM_NUM

1457607

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

DRUG BANK

DB00731

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

EPA CompTox

DTXSID9040687

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

DRUG CENTRAL

1886

Created by admin on Fri Dec 15 16:16:10 UTC 2023 , Edited by admin on Fri Dec 15 16:16:10 UTC 2023

PRIMARY

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					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					8RT5G5EY5Z

ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8

TARGET -> INHIBITOR


					E9V3S85RHY

ENANTIOMER -> ENANTIOMER

Amount:


					3FJ2FTH4UQ

MONOCARBOXYLATE TRANSPORTER 6

TRANSPORTER -> SUBSTRATE


					41X3PWK4O2

EXCRETED UNCHANGED

Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:

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					0I0E1W80TU

N-((TRANS-4-(1-HYDROXY-1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

METABOLITE -> PARENT

Interaction Type:

MAJOR


					P17J6R22FW

N-((TRANS-4-((1R)-1,2-DIHYDROXY-1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

METABOLITE -> PARENT

Qualification:

PLASMA


					FOR2T39067

N-((TRANS-4-(1-METHYLETHENYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

METABOLITE ACTIVE -> PARENT

Qualification:

PLASMA


					QQX94P5FVU

NATEGLINIDE ACYL GLUCURONIDE

METABOLITE -> PARENT


					N364WXG0U3

N-((TRANS-4-((1S)-2-HYDROXY-1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

METABOLITE -> PARENT


					C26R5S31X9

N-((TRANS-4-((1R)-2-HYDROXY-1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

METABOLITE -> PARENT

Related Record Type Details


					K4529956QE

4-DESISOPROPYL-4-ETHYL NATEGLINIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					47E5O17Y3R

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					XC84TK3YA9

D-PHENYLALANYL NATEGLINIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					E9V3S85RHY

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					XTM4DQP5S5

N-((CIS-4-(1-METHYLETHYL)CYCLOHEXYL)CARBONYL)-D-PHENYLALANINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					J76GYT4RZX

TRANS-4-ISOPROPYLCYCLOHEXANECARBOXYLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					XX9D77CLB2

ETHYL NATEGLINIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					41X3PWK4O2

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION