SARIZOTAN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H21FN2O
Molecular Weight	348.4133
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SARIZOTAN

Structure Search

SMILES

FC1=CC=C(C=C1)C2=CN=CC(CNC[C@H]3CCC4=C(O3)C=CC=C4)=C2

InChI

InChIKey=HKFMQJUJWSFOLY-OAQYLSRUSA-N

InChI=1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,15H2/t21-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H21FN2O
Molecular Weight	348.4133
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:01:11 UTC 2023` Edited by `admin` on `Fri Dec 15 16:01:11 UTC 2023`
Record UNII	467LU0UCUW
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SARIZOTAN

Official Name

English

3-PYRIDINEMETHANAMINE, 5-(4-FLUOROPHENYL)-N-(((2R)-3,4,4A,8A-TETRAHYDRO-2H-1-BENZOPYRAN-2-YL)METHYL)-

Common Name

English

SARIZOTAN [MI]

Common Name

English

EMD-77697

Code

English

3-PYRIDINEMETHANAMINE, N-(((2R)-3,4-DIHYDRO-2H-1-BENZOPYRAN-2-YL)METHYL)-5-(4-FLUOROPHENYL)-

Systematic Name

English

Sarizotan [WHO-DD]

Common Name

English

sarizotan [INN]

Common Name

English

1-(5-(4-FLUOROPHENYL)PYRIDIN-3-YL)-N-((2R)-3,4,4A,8A-TETRAHYDRO-2H-CHROMEN-2-YLMETHYL)METHANAMINE

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

484015

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

NCI_THESAURUS

C1509

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL220808

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

INN

7748

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

NCI_THESAURUS

C77567

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

SMS_ID

100000084927

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

CAS

351862-32-3

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

MESH

C443959

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

DRUG BANK

DB06454

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

WIKIPEDIA

Sarizotan

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

PUBCHEM

6918388

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

MERCK INDEX

m9782

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

Merck Index

FDA UNII

467LU0UCUW

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

EPA CompTox

DTXSID80956632

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

EVMPD

SUB04329MIG

Created by admin on Fri Dec 15 16:01:11 UTC 2023 , Edited by admin on Fri Dec 15 16:01:11 UTC 2023

PRIMARY

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Interaction Type:

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Amount:


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METABOLITE -> PARENT

Comments:

to be confirm by NMR

Amount:

Related Record Type Details


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SARIZOTAN

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC