TRICLABENDAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H9Cl3N2OS
Molecular Weight	359.658
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRICLABENDAZOLE

Structure Search

SMILES

CSC1=NC2=CC(Cl)=C(OC3=C(Cl)C(Cl)=CC=C3)C=C2N1

InChI

InChIKey=NQPDXQQQCQDHHW-UHFFFAOYSA-N

InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C14H9Cl3N2OS
Molecular Weight	359.658
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:24:23 UTC 2023` Edited by `admin` on `Fri Dec 15 16:24:23 UTC 2023`
Record UNII	4784C8E03O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRICLABENDAZOLE

Official Name

English

1H-BENZIMIDAZOLE, 6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-

Systematic Name

English

NVP-EGA230

Code

English

Triclabendazole [WHO-DD]

Common Name

English

TRICLABENDAZOLE [MART.]

Common Name

English

TRICLABENDAZOLE [ORANGE BOOK]

Common Name

English

EGATEN

Brand Name

English

triclabendazole [INN]

Common Name

English

EGA230B

Code

English

TRICLABENDAZOLE [MI]

Common Name

English

5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole

Systematic Name

English

FASINEX

Brand Name

English

TRICLABENDAZOLE [USAN]

Common Name

English

NSC-759250

Code

English

Classification Tree Code System Code

WHO-VATC

QP52AC01

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

WHO-ATC

P02BX04

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

FDA ORPHAN DRUG

564216

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.1.3

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

NCI_THESAURUS

C250

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

FDA ORPHAN DRUG

525416

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

Code System Code Type Description

CAS

68786-66-3

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

EVMPD

SUB11267MIG

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

NCI_THESAURUS

C75236

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

SMS_ID

100000092537

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

MERCK INDEX

m11087

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

Merck Index

MESH

C039276

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

DRUG CENTRAL

2734

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

EPA CompTox

DTXSID7043952

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

NSC

759250

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

RXCUI

2118525

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

LACTMED

Triclabendazole

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

FDA UNII

4784C8E03O

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

DRUG BANK

DB12245

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

ChEMBL

CHEMBL1086440

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

PUBCHEM

50248

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

DAILYMED

4784C8E03O

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

USAN

EF-110

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

INN

5003

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

RS_ITEM_NUM

1681611

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

WIKIPEDIA

TRICLABENDAZOLE

Created by admin on Fri Dec 15 16:24:23 UTC 2023 , Edited by admin on Fri Dec 15 16:24:23 UTC 2023

PRIMARY

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					VK4SQL11C0

CYTOCHROME P450 1A2

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CYTOCHROME P450 2C8

METABOLIC ENZYME -> SUBSTRATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE


					DT53URI4O9

FASCIOLA HEPATICA

TARGET ORGANISM->INHIBITOR


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> SUBSTRATE


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE


					246D9TQ2XG

CYTOCHROME P450 2A6

METABOLIC ENZYME -> INHIBITOR


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE


					PD6N2O0M3A

FASCIOLA GIGANTICA

TARGET ORGANISM->INHIBITOR


					9DX651UO0D

CYTOCHROME P450 1A1

METABOLIC ENZYME -> SUBSTRATE

Amount:


					0OZF0UI2AQ

CYTOCHROME P450 1B1

METABOLIC ENZYME -> SUBSTRATE


					9971WH3C6O

FETAL HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 3 (HUMAN)

METABOLIC ENZYME -> SUBSTRATE

Related Record Type Details


					D7KM923JRE

TRICLABENDAZOLE SULFONE

METABOLITE ACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA


					KY3O5E011U

TRICLABENDAZOLE SULFOXIDE

METABOLITE ACTIVE -> PARENT

Interaction Type:

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Qualification:

PLASMA


					ZB9HO25QQB

5-CHLORO-6-(2,3-DICHLOROPHENOXY)-1H-BENZIMIDAZOLE-2-THIOL

METABOLITE -> PARENT

Related Record Type Details


					KY3O5E011U

TRICLABENDAZOLE SULFOXIDE

IMPURITY -> PARENT

Comments:

FOR VETERINARY USE

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					81RQU2EH3K

4-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-NITROANILINE

IMPURITY -> PARENT

Comments:

FOR VETERINARY USE

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					ZB9HO25QQB

5-CHLORO-6-(2,3-DICHLOROPHENOXY)-1H-BENZIMIDAZOLE-2-THIOL

IMPURITY -> PARENT

Comments:

FOR VETERINARY USE

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					4784C8E03O

TRICLABENDAZOLE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC