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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H28O5
Molecular Weight 360.444
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALDOSTERONE

SMILES

[H][C@@]12CC[C@H](C(=O)CO)[C@]1(C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)CC[C@]34C)C=O

InChI

InChIKey=PQSUYGKTWSAVDQ-ZVIOFETBSA-N
InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

HIDE SMILES / InChI
Molecular Formula C21H28O5
Molecular Weight 360.444
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:12:15 UTC 2023
Edited
by admin
on Fri Dec 15 15:12:15 UTC 2023
Record UNII
4964P6T9RB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALDOSTERONE
INN   MART.   MI   WHO-DD  
INN  
Official Name English
ALDOSTERONE [MI]
Common Name English
aldosterone [INN]
Common Name English
Aldosterone [WHO-DD]
Common Name English
ALDOSTERONE [MART.]
Common Name English
NSC-73856
Code English
11.BETA.,21-DIHYDROXYPREGN-4-ENE-3,18,20-TRIONE
Systematic Name English
Classification Tree Code System Code
LOINC 92896-0
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 34231-1
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
NCI_THESAURUS C2324
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 1765-7
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 13482-5
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 30894-0
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 35185-8
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 1762-4
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 25845-9
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
WHO-ATC H02AA01
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 1764-0
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 31992-1
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 41023-3
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 14587-0
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 92897-8
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 35186-6
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 15010-2
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 1763-2
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
CFR 21 CFR 862.1045
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
WHO-VATC QH02AA01
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 14586-2
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
LOINC 44295-4
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
Code System Code Type Description
CAS
52-39-1
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
EPA CompTox
DTXSID7022419
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
DAILYMED
4964P6T9RB
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
EVMPD
SUB05306MIG
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
PUBCHEM
5839
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
SMS_ID
100000087869
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
NCI_THESAURUS
C219
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
CAS
6251-69-0
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
ALTERNATIVE
FDA UNII
4964P6T9RB
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
ChEMBL
CHEMBL273453
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
MERCK INDEX
m1488
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY Merck Index
CHEBI
30834
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
DRUG CENTRAL
111
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
NSC
73856
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
CHEBI
27584
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
MESH
D000450
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
WIKIPEDIA
ALDOSTERONE
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
DRUG BANK
DB04630
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
INN
483
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-139-9
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY
RXCUI
1312358
Created by admin on Fri Dec 15 15:12:15 UTC 2023 , Edited by admin on Fri Dec 15 15:12:15 UTC 2023
PRIMARY RxNorm
Related Record Type Details
MINERALOCORTICOID RECEPTOR
TARGET -> AGONIST
Related Record Type Details
Structure of 5.ALPHA.-DIHYDROALDOSTERONE
METABOLITE LESS ACTIVE -> PARENT
A clear hierarchy of antinatriuretic activity, aldosterone > 5.alpha.-DHA > 3.alpha.,5.alpha-THA > 3.alpha.,5.beta.-THA > 3.beta.,5.alpha.-THA > 5.beta.-DHA > 3.beta.,5.beta.-THA was observed
Structure of 3.ALPHA.,5.ALPHA.-TETRAHYDROALDOSTERONE
METABOLITE LESS ACTIVE -> PARENT
A clear hierarchy of antinatriuretic activity, aldosterone > 5.alpha.-DHA > 3.alpha.,5.alpha-THA > 3.alpha.,5.beta.-THA > 3.beta.,5.alpha.-THA > 5.beta.-DHA > 3.beta.,5.beta.-THA was observed
Related Record Type Details
Structure of ALDOSTERONE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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