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Details

Stereochemistry ABSOLUTE
Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIBAVIRIN

SMILES

NC(=O)C1=NN(C=N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N
InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

HIDE SMILES / InChI
Molecular Formula C8H12N4O5
Molecular Weight 244.2047
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:35:07 UTC 2023
Edited
by admin
on Fri Dec 15 15:35:07 UTC 2023
Record UNII
49717AWG6K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RIBAVIRIN
EMA EPAR   EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
COPEGUS
Brand Name English
COTRONAK
Brand Name English
RIBAVIRIN [USP MONOGRAPH]
Common Name English
RBV
Common Name English
ribavirin [INN]
Common Name English
1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE, 1-.BETA.-D-RIBOFURANOSYL-
Common Name English
RIBAVIRIN [HSDB]
Common Name English
RIBAVIRIN [EMA EPAR]
Common Name English
SCH 18908
Code English
SCH-18908
Code English
Ribavirin [WHO-DD]
Common Name English
NSC-163039
Code English
RIBAVIRIN BIOPARTNERS
Brand Name English
RIBAVIRIN [MI]
Common Name English
RIBAVIRIN TEVA PHARMA B.V.
Brand Name English
REBETOL
Brand Name English
RIBAVIRIN MYLAN
Brand Name English
RIBAVIRIN [EP MONOGRAPH]
Common Name English
RIBAVIRIN [VANDF]
Common Name English
RIBAVIRIN [JAN]
Common Name English
RIBAVIRIN [MART.]
Common Name English
RIBAVIRIN [ORANGE BOOK]
Common Name English
RIBAVIRIN COMPONENT OF PEGINTERFERON
Common Name English
VIRAZOLE
Brand Name English
RIBASPHERE
Brand Name English
RIBAVIRIN [USAN]
Common Name English
RIBAVIRIN TEVA
Brand Name English
1-.BETA.-D-RIBOFURANOSYL-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
Common Name English
RIBAVIRIN [USP-RS]
Common Name English
Classification Tree Code System Code
NDF-RT N0000175466
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS RIBAVIRIN TEVA (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
WHO-ATC J05AP01
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
FDA ORPHAN DRUG 57491
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS RIBAVIRIN TEVA PHARMA B.V. (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
LIVERTOX NBK548115
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
WHO-VATC QJ05AB04
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS COTRONAK (REFUSED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EU-Orphan Drug EU/3/01/024
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.4.3
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
NCI_THESAURUS C281
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS REBETOL (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
WHO-ATC J05AB04
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
NDF-RT N0000175459
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS RIBAVIRIN BIOPARTNERS (WITHDRAWN: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
FDA ORPHAN DRUG 162402
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
EMA ASSESSMENT REPORTS RIBAVIRIN MYLAN (AUTHORIZED: HEPATITIS C, CHRONIC)
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
Code System Code Type Description
NSC
163039
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
NCI_THESAURUS
C807
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
INN
3543
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
ChEMBL
CHEMBL1643
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
SMS_ID
100000089166
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
MESH
D012254
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
CAS
36791-04-5
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
RS_ITEM_NUM
1602706
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
EVMPD
SUB10297MIG
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
JAPANESE REVIEW
COPEGUS
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY APPROVED MARCH 2015
LACTMED
Ribavirin
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
MERCK INDEX
m9593
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID8023557
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
CHEBI
63580
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
DRUG BANK
DB00811
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
HSDB
6513
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
ALANWOOD
ribavirin
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
IUPHAR
6842
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
CAS
66510-90-5
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
SUPERSEDED
RXCUI
9344
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY RxNorm
WIKIPEDIA
RIBAVIRIN
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
FDA UNII
49717AWG6K
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
DRUG CENTRAL
2373
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
PUBCHEM
37542
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
DAILYMED
49717AWG6K
Created by admin on Fri Dec 15 15:35:07 UTC 2023 , Edited by admin on Fri Dec 15 15:35:07 UTC 2023
PRIMARY
Related Record Type Details
Structure of RIBAVIRIN
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
SARS-COV2
TARGET ORGANISM->INHIBITOR
A guanine derivative approved for treating HCV and respiratory syncytial virus (RSV) that has been evaluated in patients with SARS and MERS, but its side effects such as anaemia may be severe at high doses.
Structure of RIBAVIRIN
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
RNA-DEPENDENT RNA POLYMERASE COMPLEX (COVID 2019 VIRUS)
TARGET -> INHIBITOR
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1
TARGET -> INHIBITOR
Related Record Type Details
Structure of 1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID
METABOLITE -> PARENT
a degradative pathway involving deribosylation and amide hydrolysis to yield a triazole carboxylic acid metabolite; Excreted renally
Structure of RIBAVIRIN 5'-PHOSPHATE
METABOLITE -> PARENT
BY adenosine kinase
Structure of 1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
METABOLITE -> PARENT
a degradative pathway involving deribosylation and amide hydrolysis to yield a triazole carboxylic acid metabolite; excreted renally.
Structure of TARIBAVIRIN
PRODRUG -> METABOLITE ACTIVE
Structure of RIBAVIRIN TRIPHOSPHATE
METABOLITE -> PARENT
by the successive action of nucleoside mono- and di-phosphate kinases
MAJOR
PLASMA
Related Record Type Details
Structure of 1-.BETA.-D-RIBOFURANOSYL-1H-1,2,4-TRIAZOLE-5-CARBOXAMIDE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of RIBAVIRIN CARBOXYLIC ACID
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 2.3
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of RIBAVIRIN METHYL ESTER
IMPURITY -> PARENT
Structure of 1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of .ALPHA.-RIBAVIRIN
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of RIBAVIRIN 5'-BENZOYL
IMPURITY -> PARENT
Structure of 5'-O-ACETYLRIBAVIRIN
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID
IMPURITY -> PARENT
UNSPECIFIED
EP
Related Record Type Details
Structure of RIBAVIRIN
ACTIVE MOIETY
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