PITOLISANT

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H26ClNO
Molecular Weight	295.847
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PITOLISANT

Structure Search

SMILES

ClC1=CC=C(CCCOCCCN2CCCCC2)C=C1

InChI

InChIKey=NNACHAUCXXVJSP-UHFFFAOYSA-N

InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2

HIDE SMILES / InChI

Molecular Formula	C17H26ClNO
Molecular Weight	295.847
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:35:11 UTC 2023` Edited by `admin` on `Sat Dec 16 01:35:11 UTC 2023`
Record UNII	4BC83L4PIY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PITOLISANT

Official Name

English

BF2.649

Code

English

HBS-101

Code

English

PITOLISANT [USAN]

Common Name

English

PITOLISANT [MI]

Common Name

English

3-(4-CHLOROPHENYL)PROPYL 3-PIPERIDINOPROPYL ETHER

Systematic Name

English

1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine

Systematic Name

English

Pitolisant [WHO-DD]

Common Name

English

pitolisant [INN]

Common Name

English

BF-2.649

Code

English

PIPERIDINE, 1-(3-(3-(4-CHLOROPHENYL)PROPOXY)PROPYL)-

Systematic Name

English

BF-2649

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

307210

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

WHO-ATC

N07XX11

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID30957654

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

SMS_ID

100000161112

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

ChEMBL

CHEMBL462605

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

DAILYMED

4BC83L4PIY

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

MERCK INDEX

m11944

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

EVMPD

SUB174467

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

INN

8952

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

FDA UNII

4BC83L4PIY

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

RXCUI

2197878

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

NCI_THESAURUS

C166747

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

EVMPD

SUB166257

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

PUBCHEM

9948102

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

DRUG BANK

DB11642

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

WIKIPEDIA

PITOLISANT

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

USAN

FG-186

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

MESH

C516975

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

DRUG CENTRAL

5048

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

CAS

362665-56-3

Created by admin on Sat Dec 16 01:35:11 UTC 2023 , Edited by admin on Sat Dec 16 01:35:11 UTC 2023

PRIMARY

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Comments:

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Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:


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METABOLITE -> PARENT


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					92HJ692NVA

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METABOLITE INACTIVE -> PARENT

Interaction Type:

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Qualification:

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					PZJ8U47GCC

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Interaction Type:

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Qualification:

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					J97448L6PV

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METABOLITE -> PARENT


					979AKY5CZX

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METABOLITE -> PARENT

Related Record Type Details


					4BC83L4PIY

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
blood to plasma ratio	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				SINGLE DOSE ADMINISTRATION

Volume of Distribution	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				DOSE ORAL ADMINISTRATION ONCE DAILY