KETOROLAC TROMETHAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H13NO3.C4H11NO3
Molecular Weight	376.4037
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of KETOROLAC TROMETHAMINE

Structure Search

SMILES

NC(CO)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C3=CC=CC=C3

InChI

InChIKey=BWHLPLXXIDYSNW-UHFFFAOYSA-N

InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2

HIDE SMILES / InChI

Molecular Formula	C4H11NO3
Molecular Weight	121.135
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C15H13NO3
Molecular Weight	255.2686
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:36:52 UTC 2023` Edited by `admin` on `Fri Dec 15 15:36:52 UTC 2023`
Record UNII	4EVE5946BQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

KETOROLAC TROMETHAMINE

Official Name

English

OMIDRIA COMPONENT KETOROLAC TROMETHAMINE

Brand Name

English

(±)-5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLIC ACID, COMPOUND WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)

Common Name

English

LIXIDOL

Brand Name

English

KETOROLAC TROMETAMOL [JAN]

Common Name

English

KETOROLAC TROMETHAMINE [USP MONOGRAPH]

Common Name

English

ACULAR

Brand Name

English

KETOROLAC TROMETHAMINE COMPONENT OF OMIDRIA

Brand Name

English

KETOROLAC TROMETAMOL

Common Name

English

ACUVAIL

Brand Name

English

TARASYN

Brand Name

English

2-AMINO-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL (1RS)-5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLATE

Systematic Name

English

NSC-758637

Code

English

KETOROLAC TROMETHAMINE [USP-RS]

Common Name

English

1H-PYRROLIZINE-1-1H-PYRROLIZINE-1-CARBOXYLIC ACID, 5-BENZOYL-2,3-DIHYDRO, (±)-, COMPOUND WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)

Common Name

English

Ketorolac tromethamine [WHO-DD]

Common Name

English

KETOROLAC TROMETHAMINE [USAN]

Common Name

English

DOLAC

Brand Name

English

KETOROLAC (±)-FORM TROMETHAMINE SALT [MI]

Common Name

English

KETOROLAC TROMETHAMINE [VANDF]

Common Name

English

TORADOL

Brand Name

English

KETOROLAC TROMETHAMINE [ORANGE BOOK]

Common Name

English

SPRIX

Brand Name

English

KETOROLAC TROMETAMOL [EP MONOGRAPH]

Common Name

English

KETOROLAC TROMETAMOL [MART.]

Common Name

English

2-AMINO-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL; 5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLIC ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1323

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C61798

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

EVMPD

SUB02835MIG

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

PUBCHEM

84003

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

FDA UNII

4EVE5946BQ

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

ChEMBL

CHEMBL469

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

EPA CompTox

DTXSID0045597

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

USAN

T-104

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

RS_ITEM_NUM

1356665

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

CHEBI

6130

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

DRUG BANK

DBSALT001045

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

CAS

74103-07-4

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

SMS_ID

100000091653

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

RXCUI

28200

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

RxNorm

MESH

D020911

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

DAILYMED

4EVE5946BQ

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

MERCK INDEX

m6623

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

Merck Index

NSC

758637

Created by admin on Fri Dec 15 15:36:52 UTC 2023 , Edited by admin on Fri Dec 15 15:36:52 UTC 2023

PRIMARY

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KETOROLAC TROMETHAMINE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

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Amount:


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KETOROLAC TROMETHAMINE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

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Qualification:

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Amount:


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KETOROLAC TROMETHAMINE, (S)-

ENANTIOMER -> RACEMATE

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					AD3BGE2V2U

5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZIN-1-ONE

IMPURITY -> PARENT

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Qualification:

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Amount:


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5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZIN-1-OL, (±)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

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Amount:


					89S33ZWH0R

1H-PYRROLIZINE-1-CARBOXAMIDE, 5-BENZOYL-2,3-DIHYDRO-N-(2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL)-, (±)-

IMPURITY -> PARENT


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KETOROLAC ETHYL ESTER

IMPURITY -> PARENT

Comments:

unspecified

Interaction Type:

UNKNOWN

Qualification:

EP


					1E6HRS114R

5-BENZOYL-1-METHOXY-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLIC ACID, (±)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


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METHYL 5-BENZOYL-1-HYDROXY2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLATE, (±)-

IMPURITY -> PARENT

Comments:

unspecified

Interaction Type:

UNKNOWN

Qualification:

EP


					Y1N9717B7S

5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZIN-1-OL, (±)-

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 0.67

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					AD3BGE2V2U

5-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZIN-1-ONE

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 0.52

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Z04JK222T5

6-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLIC ACID, (±)-

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 2.2

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					5R8UQ90JO4

7-BENZOYL-2,3-DIHYDRO-1H-PYRROLIZINE-1-CARBOXYLIC ACID, (±)-

IMPURITY -> PARENT

Comments:

unspecified

Interaction Type:

UNKNOWN

Qualification:

EP


					9C0MT6TTH9

PHENYL(2,3-DIHYDRO-1H-PYRROLIZIN-5-YL)METHANONE

IMPURITY -> PARENT

Comments:

unspecified

Interaction Type:

UNKNOWN

Qualification:

EP


					884M437C95

KETOROLAC METHYL ESTER

IMPURITY -> PARENT

Comments:

unspecified

Interaction Type:

UNKNOWN

Qualification:

EP

Related Record Type Details


					YZI5105V0L

KETOROLAC

ACTIVE MOIETY