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Details

Stereochemistry ABSOLUTE
Molecular Formula C28H30N4O6
Molecular Weight 518.561
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LURTOTECAN

SMILES

CC[C@@]1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=C6OCCOC6=CC5=C4CN7CCN(C)CC7)C2=O

InChI

InChIKey=RVFGKBWWUQOIOU-NDEPHWFRSA-N
InChI=1S/C28H30N4O6/c1-3-28(35)20-11-22-25-18(14-32(22)26(33)19(20)15-38-27(28)34)17(13-31-6-4-30(2)5-7-31)16-10-23-24(12-21(16)29-25)37-9-8-36-23/h10-12,35H,3-9,13-15H2,1-2H3/t28-/m0/s1

HIDE SMILES / InChI
Molecular Formula C28H30N4O6
Molecular Weight 518.561
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:14:55 UTC 2023
Edited
by admin
on Sat Dec 16 17:14:55 UTC 2023
Record UNII
4J1L80T08I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LURTOTECAN
INN  
INN  
Official Name English
(8S)-8-ETHYL-2,3-DIHYDRO-8-HYDROXY-15-((4-METHYL-1-PIPERAZINYL)METHYL)-11H-P-DIOXINO(2,3-G)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-9,12(8H,14H)-DIONE
Common Name English
11H-1,4-DIOXINO(2,3-G)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-9,12(8H,14H)-DIONE, 8-ETHYL-2,3-DIHYDRO-8-HYDROXY-15-((4-METHYL-1-PIPERAZINYL)METHYL)-, (S)
Common Name English
lurtotecan [INN]
Common Name English
Lurtotecan [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2843
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
Code System Code Type Description
MESH
C091719
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
NCI_THESAURUS
C1610
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
SMS_ID
100000082293
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
EVMPD
SUB08622MIG
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
DRUG BANK
DB12222
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
ChEMBL
CHEMBL305666
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
PUBCHEM
60956
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
INN
7402
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
FDA UNII
4J1L80T08I
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
WIKIPEDIA
LURTOTECAN
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
CAS
149882-10-0
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
EPA CompTox
DTXSID30164422
Created by admin on Sat Dec 16 17:14:56 UTC 2023 , Edited by admin on Sat Dec 16 17:14:56 UTC 2023
PRIMARY
Related Record Type Details
DNA TOPOISOMERASE 1
TARGET -> INHIBITOR
Structure of LURTOTECAN DIHYDROCHLORIDE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of LURTOTECAN
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