NALOXONE HYDROCHLORIDE DIHYDRATE

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H21NO4.ClH.2H2O
Molecular Weight	399.866
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NALOXONE HYDROCHLORIDE DIHYDRATE

Structure Search

SMILES

O.O.Cl.[H][C@@]12OC3=C4C(C[C@H]5N(CC=C)CC[C@@]14[C@@]5(O)CCC2=O)=CC=C3O

InChI

InChIKey=TXMZWEASFRBVKY-IOQDSZRYSA-N

InChI=1S/C19H21NO4.ClH.2H2O/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;;;/h2-4,14,17,21,23H,1,5-10H2;1H;2*1H2/t14-,17+,18+,19-;;;/m1.../s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C19H21NO4
Molecular Weight	327.3743
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:59:28 UTC 2023` Edited by `admin` on `Fri Dec 15 14:59:28 UTC 2023`
Record UNII	5Q187997EE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NALOXONE HYDROCHLORIDE DIHYDRATE

Common Name

English

(-)-N-ALLYL-14-HYDROXYNORDIHYDROMORPHINONE HYDROCHLORIDE DIHYDRATE

Common Name

English

NALOXONE CHLORHYDRATE

Common Name

English

NALOXONE HYDROCHLORIDE DIHYDRATE [MI]

Common Name

English

NALOXONE HYDROCHLORIDE DIHYDRATE COMPONENT OF BUNAVAIL

Brand Name

English

BUNAVAIL COMPONENT NALOXONE HYDROCHLORIDE DIHYDRATE

Brand Name

English

17-ALLYL-4,5.ALPHA.-EPOXY-3,14-DIHYDROXYMORPHINAN-6-ONE HYDROCHLORIDE DIHYDRATE

Systematic Name

English

NALOXONI HYDROCHLORIDUM DIHYDRATE [WHO-IP LATIN]

Common Name

English

CASSIPA COMPONENT NALOXONE HYDROCHLORIDE DIHYDRATE

Brand Name

English

NALOXONE HYDROCHLORIDE DIHYDRATE COMPONENT OF CASSIPA

Brand Name

English

NALOXONE HYDROCHLORIDE DIHYDRATE [EP MONOGRAPH]

Common Name

English

NALOXONE HYDROCHLORIDE DIHYDRATE [WHO-IP]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/12/1057

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

Code System Code Type Description

RXCUI

1010598

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

RxNorm

DAILYMED

5Q187997EE

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

MERCK INDEX

m7717

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

EPA CompTox

DTXSID90199452

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

NALOXONE HYDROCHLORIDE DIHYDRATE

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

Description: A white or almost white powder. Solubility: Soluble in water; slightly soluble in ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Narcotic antagonist. Storage: Naloxone hydrochloride should be kept in a tightly closed container, protected from light. Labelling: The designation on the container of Naloxone hydrochloride should state whether the substance is in the anhydrous form or is the dihydrate. Additional information: Even in the absence of light, Naloxone hydrochloride is gradually degraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. It melts at about 177?C.

SMS_ID

100000089225

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

CAS

51481-60-8

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

EVMPD

SUB12168MIG

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

FDA UNII

5Q187997EE

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

DRUG BANK

DBSALT001497

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

PUBCHEM

20112022

Created by admin on Fri Dec 15 14:59:28 UTC 2023 , Edited by admin on Fri Dec 15 14:59:28 UTC 2023

PRIMARY

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