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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H21NO4.ClH
Molecular Weight 363.835
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NALOXONE HYDROCHLORIDE

SMILES

Cl.[H][C@@]12OC3=C4C(C[C@H]5N(CC=C)CC[C@@]14[C@@]5(O)CCC2=O)=CC=C3O

InChI

InChIKey=RGPDIGOSVORSAK-STHHAXOLSA-N
InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1

HIDE SMILES / InChI
Molecular Formula C19H21NO4
Molecular Weight 327.3743
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:09:13 UTC 2023
Edited
by admin
on Fri Dec 15 15:09:13 UTC 2023
Record UNII
F850569PQR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NALOXONE HYDROCHLORIDE
GREEN BOOK   MART.   MI   ORANGE BOOK   USAN   USP   VANDF   WHO-DD  
USAN  
Official Name English
ANHYDROUS NALOXONE HYDROCHLORIDE
Common Name English
NALOXONE HYDROCHLORIDE [JAN]
Common Name English
NALOXONE HYDROCHLORIDE COMPONENT OF SUBOXONE
Common Name English
NARCANTI
Common Name English
EN-15304
Code English
NALOXONE HYDROCHLORIDE [MART.]
Common Name English
NALOXONE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
NALOXONE HYDROCHLORIDE [MI]
Common Name English
(-)-N-ALLYL-14-HYDROXYNORDIHYDROMORPHINONE HYDROCHLORIDE
Common Name English
RIVIVE
Brand Name English
NALOXONE HCL
Common Name English
NALOXONE HYDROCHLORIDE [GREEN BOOK]
Common Name English
TARGINIQ COMPONENT NALOXONE HYDROCHLORIDE
Brand Name English
NALOXONE HYDROCHLORIDE [VANDF]
Common Name English
MORPHINAN-6-ONE, 4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPENYL)-, HYDROCHLORIDE, (5.ALPHA.)-
Systematic Name English
TALWIN NX COMPONENT NALOXONE HYDROCHLORIDE
Common Name English
Naloxone hydrochloride [WHO-DD]
Common Name English
NSC-757109
Code English
NARCAN
Brand Name English
NALOXONE HYDROCHLORIDE COMPONENT OF TARGINIQ
Brand Name English
NALOXONE HYDROCHLORIDE [USAN]
Common Name English
NALOXONE HYDROCHLORIDE ANHYDROUS [WHO-IP]
Common Name English
EVZIO
Brand Name English
NALOXONE HYDROCHLORIDE COMPONENT OF TALWIN NX
Common Name English
17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
Systematic Name English
NALOXONE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
NALOXONI HYDROCHLORIDUM ANHYDROUS [WHO-IP LATIN]
Common Name English
SUBOXONE COMPONENT NALOXONE HYDROCHLORIDE
Common Name English
NIH 7890
Code English
KLOXXADO
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C681
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
Code System Code Type Description
SMS_ID
100000091649
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
NCI_THESAURUS
C678
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
RXCUI
203192
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY RxNorm
EVMPD
SUB03382MIG
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
CAS
357-08-4
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
EPA CompTox
DTXSID70957097
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
FDA UNII
F850569PQR
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
NSC
757109
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
DRUG BANK
DBSALT000126
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
ECHA (EC/EINECS)
206-611-0
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
MERCK INDEX
m7717
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY Merck Index
ChEMBL
CHEMBL80
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
PUBCHEM
5464092
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
CHEBI
31892
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
NALOXONE HYDROCHLORIDE
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY Description: A white or almost white powder. Solubility: Soluble in water; slightly soluble in ethanol (~750 g/l) TS; practically insoluble in ether R.Category: Narcotic antagonist. Storage: Naloxone hydrochloride should be kept in a tightly closed container, protected from light. Labelling: The designation on the container of Naloxone hydrochloride should state whether the substance is in the anhydrousform or is the dihydrate. Additional information: Even in the absence of light, Naloxone hydrochloride is gradually degraded on exposure to a humidatmosphere, the decomposition being faster at higher temperatures. It melts at about 177?C. Definition: Naloxone hydrochloride contains not less than 98.0% and not more than 102.0% of C19H21NO4,HCl, calculated withreference to the dried substance.
EVMPD
SUB25206
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
DAILYMED
F850569PQR
Created by admin on Fri Dec 15 15:09:13 UTC 2023 , Edited by admin on Fri Dec 15 15:09:13 UTC 2023
PRIMARY
Related Record Type Details
Structure of NALOXONE HYDROCHLORIDE DIHYDRATE
SOLVATE->ANHYDROUS
Structure of NALOXONE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of NALOXONE
ACTIVE MOIETY
NIH
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