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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H23NO4
Molecular Weight 341.4009
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NALTREXONE

SMILES

[H][C@@]12OC3=C4C(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CCC2=O)=CC=C3O

InChI

InChIKey=DQCKKXVULJGBQN-XFWGSAIBSA-N
InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1

HIDE SMILES / InChI
Molecular Formula C20H23NO4
Molecular Weight 341.4009
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:31:41 UTC 2023
Edited
by admin
on Sat Dec 16 17:31:41 UTC 2023
Record UNII
5S6W795CQM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NALTREXONE
HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
EN-1639A FREE BASE
Code English
NALTREXONE [VANDF]
Common Name English
NALTREXONE [USP-RS]
Common Name English
naltrexone [INN]
Common Name English
Naltrexone [WHO-DD]
Common Name English
17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one
Systematic Name English
NALTREXONE [HSDB]
Common Name English
NALTREXONE [ORANGE BOOK]
Common Name English
NALTREXONE COMPONENT OF CONTRAVE
Brand Name English
MORPHINAN-6-ONE, 17-(CYCLOPROPYLMETHYL)-4,5-EPOXY-3,14-DIHYDROXY-, (5.ALPHA.)-
Systematic Name English
NALTREXONE [MI]
Common Name English
NSC-758439
Code English
NALTREXONE [USAN]
Common Name English
VIVITROL
Brand Name English
NALTREXONE [MART.]
Common Name English
Classification Tree Code System Code
LIVERTOX NBK559444
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
EU-Orphan Drug Naltrexone
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
WHO-ATC N02AA56
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
WHO-ATC A08AA62
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
LIVERTOX NBK548583
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 425614
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
NDF-RT N0000175691
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 819621
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 465614
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 422914
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 296909
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
WHO-ATC N07BB04
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
NCI_THESAURUS C681
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
WHO-VATC QN07BB04
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
NDF-RT N0000000154
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
FDA ORPHAN DRUG 460314
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
WHO-ATC N02AA56
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
Code System Code Type Description
NSC
758439
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
SMS_ID
100000084462
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
PUBCHEM
5360515
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
EPA CompTox
DTXSID4046313
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
EVMPD
SUB09143MIG
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
CHEBI
7465
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
RS_ITEM_NUM
1453504
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
DAILYMED
5S6W795CQM
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
HSDB
6750
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
DRUG CENTRAL
1765
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
MERCK INDEX
m7718
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
240-649-9
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
CAS
16590-41-3
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
LACTMED
Naltrexone
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
NCI_THESAURUS
C62055
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
WIKIPEDIA
NALTREXONE
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
FDA UNII
5S6W795CQM
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
MESH
D009271
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
INN
3368
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
DRUG BANK
DB00704
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
ChEMBL
CHEMBL19019
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
IUPHAR
1639
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY
RXCUI
7243
Created by admin on Sat Dec 16 17:31:43 UTC 2023 , Edited by admin on Sat Dec 16 17:31:43 UTC 2023
PRIMARY RxNorm
Related Record Type Details
Structure of NALTREXONE HYDROCHLORIDE DIHYDRATE
SALT/SOLVATE -> PARENT
Structure of NALTREXONE BENZOATE
SALT/SOLVATE -> PARENT
Structure of NALTREXONE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
KAPPA-TYPE OPIOID RECEPTOR
TARGET -> INHIBITOR
MU-TYPE OPIOID RECEPTOR
TARGET -> INHIBITOR
Related Record Type Details
Structure of 2-HYDROXY-3-METHOXYNALTREXONE
METABOLITE -> PARENT
MINOR
URINE
Structure of 2-HYDROXY-3-METHOXY-6.BETA.-NALTREXOL
METABOLITE -> PARENT
MINOR
URINE
Structure of 6.BETA.-NALTREXOL
METABOLITE ACTIVE -> PARENT
Related Record Type Details
Structure of NALTREXONE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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